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Comparative Effectiveness Research

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Comparative effectiveness of human scope assistant versus robotic scope holder in laparoscopic resection for colorectal cancer.

Surgical endoscopy
BACKGROUND: Several types of robotic scope holders have been developed to date, but there are only some experimental reports or the results of small clinical cases. The Soloassist® system is a unique robotic scope holder with which the surgeon can co...

Comparison of Machine Learning Methods With National Cardiovascular Data Registry Models for Prediction of Risk of Bleeding After Percutaneous Coronary Intervention.

JAMA network open
IMPORTANCE: Better prediction of major bleeding after percutaneous coronary intervention (PCI) may improve clinical decisions aimed to reduce bleeding risk. Machine learning techniques, bolstered by better selection of variables, hold promise for enh...

Deep Learning-based Propensity Scores for Confounding Control in Comparative Effectiveness Research: A Large-scale, Real-world Data Study.

Epidemiology (Cambridge, Mass.)
BACKGROUND: Due to the non-randomized nature of real-world data, prognostic factors need to be balanced, which is often done by propensity scores (PSs). This study aimed to investigate whether autoencoders, which are unsupervised deep learning archit...

Comparative Effectiveness Analysis of Lumpectomy and Mastectomy for Elderly Female Breast Cancer Patients: A Deep Learning-based Big Data Analysis.

The Yale journal of biology and medicine
: To evaluate the comparative effectiveness of treatments, a randomized clinical trial remains the gold standard but can be challenged by a high cost, a limited sample size, an inability to fully reflect the real world, and feasibility concerns. The ...

R WE ready for reimbursement? A round up of developments in real-world evidence relating to health technology assessment: part 17.

Journal of comparative effectiveness research
In this update, we discuss a position statement from the National Institute of Health and Care Excellence (NICE) on the use of artificial intelligence for evidence generation and publications reviewing the use of real-world data as external control a...

Semantic Clinical Artificial Intelligence vs Native Large Language Model Performance on the USMLE.

JAMA network open
IMPORTANCE: Large language models (LLMs) are being implemented in health care. Enhanced accuracy and methods to maintain accuracy over time are needed to maximize LLM benefits.