Predictors of Nodal and Metastatic Failure in Early Stage Non-small-cell Lung Cancer After Stereotactic Body Radiation Therapy.

Journal: Clinical lung cancer
Published Date: Dec 29, 2018

Abstract

INTRODUCTION/BACKGROUND: Many patients with early stage non-small-cell lung cancer (ES-NSCLC) undergoing stereotactic body radiation therapy (SBRT) develop metastases, which is associated with poor outcomes. We sought to identify factors predictive of metastases after lung SBRT and created a risk stratification tool.

Authors

  • Alberto Cerra-Franco
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Sheng Liu
    Medical School, Xizang Minzu University, Xianyang, People's Republic of China.
  • Michella Azar
    Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN.
  • Kevin Shiue
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Samantha Freije
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Jason Hinton
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Christopher R Deig
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Donna Edwards
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Neil C Estabrook
    Department of Radiation Oncology, Indiana University Health Arnett Hospital, Lafayette, IN.
  • Susannah G Ellsworth
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Ke Huang
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Khalil Diab
    Pulmonary, Critical Care, Sleep, and Occupational Medicine, Indiana University School of Medicine, Indianapolis, IN.
  • Mark P Langer
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Richard Zellars
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Feng-Ming Kong
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN.
  • Jun Wan
    Department of Medical and Molecular Genetics, Collaborative Core for Cancer Bioinformatics, Indianapolis, IN.
  • Tim Lautenschlaeger
    Department of Radiation Oncology, Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN. Electronic address: timlaut@iupui.edu.

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