Decreased circulating catestatin levels are associated with coronary artery disease: The emerging anti-inflammatory role.

Journal: Atherosclerosis
PMID: 30658195

Abstract

BACKGROUND AND AIMS: The neuropeptide catestatin (CST) is an endogenous nicotinic cholinergic antagonist that acts as pleiotropic cardiac protective hormone. This study investigated the association between CST and coronary artery disease (CAD) and the underlying mechanisms.

Authors

  • Yanjia Chen
    The College of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Xiaoqun Wang
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
  • Chendie Yang
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
  • Xiuxiu Su
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
  • Wenbo Yang
    Institute of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
  • Yang Dai
    Institute of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
  • Hui Han
    Department of Nursing, the First People's Hospital of Huzhou, Huzhou University, Huzhou, China.
  • Jie Jiang
    Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P. R. China.
  • Lin Lu
    School of Economics and Management, Guangxi Normal University, Guilin, China.
  • Haibo Wang
    Institute of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
  • Qiujing Chen
    Institute of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
  • Wei Jin
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China; Institute of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China. Electronic address: jinwei1125@126.com.

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