AIMC Topic: Human Umbilical Vein Endothelial Cells

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Anticoagulation colloidal microrobots based on heparin-mimicking polymers.

Journal of colloid and interface science Mar 19, 2025
Coagulation within blood vessels is a major cause of cardiovascular disease and global mortality, highlighting the urgent need for effective anticoagulant strategies. In this study, we introduce a dynamic and highly efficient anticoagulant platform, ...
Cell Proliferation Particle Size Robotics Heparin Humans Polymers Surface Properties Myocytes, Smooth Muscle Colloids Anticoagulants Blood Coagulation Gold Human Umbilical Vein Endothelial Cells
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Integrative analysis of PANoptosis-related genes in diabetic retinopathy: machine learning identification and experimental validation.

Frontiers in immunology Dec 4, 2024
BACKGROUND: Diabetic retinopathy (DR) is a major complication of diabetes, leading to severe vision impairment. Understanding the molecular mechanisms, particularly PANoptosis, underlying DR is crucial for identifying potential biomarkers and therape...
ROC Curve RNA-Seq Gene Regulatory Networks Nomograms Humans Diabetic Retinopathy Machine Learning Biomarkers Phospholipid Transfer Proteins Regulated Cell Death Human Umbilical Vein Endothelial Cells Gene Expression Regulation Random Forest Molecular Targeted Therapy CD4-Positive T-Lymphocytes Memory T Cells Fatty Acid Synthase, Type I
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Large Scale Ultrafast Manufacturing of Wireless Soft Bioelectronics Enabled by Autonomous Robot Arm Printing Assisted by a Computer Vision-Enabled Guidance System for Personalized Wound Healing.

Advanced healthcare materials Nov 15, 2024
A Customized wound patch for Advanced tissue Regeneration with Electric field (CARE), featuring an autonomous robot arm printing system guided by a computer vision-enabled guidance system for fast image recognition is introduced. CARE addresses the g...
Human Umbilical Vein Endothelial Cells Wireless Technology Humans Precision Medicine Wound Healing Fibroblasts Printing, Three-Dimensional Robotics
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β-D-Glucan promotes NF-κB activation and ameliorates high-LET carbon-ion irradiation-induced human umbilical vein endothelial cell injury.

Turkish journal of medical sciences Sep 21, 2023
BACKGROUND/AIM: Heavy-ion irradiation seriously perturbs cellular homeostasis and thus damages cells. Vascular endothelial cells (ECs) play an important role in the pathological process of radiation damage. Protecting ECs from heavy-ion radiation is ...
beta-Glucans Radiation-Protective Agents Humans Apoptosis Cell Survival Reactive Oxygen Species NF-kappa B Human Umbilical Vein Endothelial Cells DNA Damage
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A machine learning approach to predict cellular mechanical stresses in response to chemical perturbation.

Biophysical journal Jul 25, 2023
Mechanical stresses generated at the cell-cell level and cell-substrate level have been suggested to be important in a host of physiological and pathological processes. However, the influence various chemical compounds have on the mechanical stresses...
Collagen Type I Mechanotransduction, Cellular Time-Lapse Imaging Chalcone Human Umbilical Vein Endothelial Cells Linear Models Stress, Mechanical Humans Machine Learning Cells, Cultured Support Vector Machine
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Anti-senescent drug screening by deep learning-based morphology senescence scoring.

Nature communications Jan 11, 2021
Advances in deep learning technology have enabled complex task solutions. The accuracy of image classification tasks has improved owing to the establishment of convolutional neural networks (CNN). Cellular senescence is a hallmark of ageing and is im...
Drug Evaluation, Preclinical beta-Galactosidase Cell Shape Deep Learning Hydrogen Peroxide Human Umbilical Vein Endothelial Cells Humans Neural Networks, Computer Cellular Senescence
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Myricitrin inhibits vascular endothelial growth factor-induced angiogenesis of human umbilical vein endothelial cells and mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Sep 17, 2020
In the present study, the protective effects of myricitrin against vascular endothelial growth factor (VEGF)-induced angiogenesis of vascular endothelial cells were characterized. Cells were induced with 50 ng/mL VEGF in the presence or absence of va...
Flavonoids Human Umbilical Vein Endothelial Cells Caspases Matrix Metalloproteinases Angiogenesis Inhibitors Humans Disease Models, Animal Apoptosis Biomarkers Neovascularization, Pathologic Animals Neovascularization, Physiologic Cell Line, Tumor Vascular Endothelial Growth Factors Mice Xenograft Model Antitumor Assays
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Shape-to-graph mapping method for efficient characterization and classification of complex geometries in biological images.

PLoS computational biology Sep 3, 2020
With the ever-increasing quality and quantity of imaging data in biomedical research comes the demand for computational methodologies that enable efficient and reliable automated extraction of the quantitative information contained within these image...
Gene Knockdown Techniques Algorithms Cell Line, Tumor Image Processing, Computer-Assisted Computational Biology Decision Trees Human Umbilical Vein Endothelial Cells Humans Cytological Techniques Machine Learning Pattern Recognition, Automated
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Machine learning uncovers cell identity regulator by histone code.

Nature communications Jun 1, 2020
Conversion between cell types, e.g., by induced expression of master transcription factors, holds great promise for cellular therapy. Our ability to manipulate cell identity is constrained by incomplete information on cell identity genes (CIGs) and t...
Phenotype RNA-Seq Gene Regulatory Networks Epigenesis, Genetic Transcription Factors Databases, Genetic Human Umbilical Vein Endothelial Cells Regenerative Medicine Humans Machine Learning Histone Code Algorithms Chromatin Immunoprecipitation Sequencing Gene Expression Regulation Cells Pluripotent Stem Cells
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Machine-Learning-Driven Surface-Enhanced Raman Scattering Optophysiology Reveals Multiplexed Metabolite Gradients Near Cells.

ACS nano Feb 12, 2019
The extracellular environment is a complex medium in which cells secrete and consume metabolites. Molecular gradients are thereby created near cells, triggering various biological and physiological responses. However, investigating these molecular gr...
HeLa Cells Fibroblasts Humans Human Umbilical Vein Endothelial Cells Machine Learning Adenosine Triphosphate Biosensing Techniques Spectrum Analysis, Raman
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