AI Medical Compendium Journal:
Clinical pharmacology and therapeutics

Showing 11 to 20 of 59 articles

A Natural Language Processing Approach Towards Harmonized Communication of Uncertainties Identified During the European Medicine Authorization Process.

Clinical pharmacology and therapeutics
Within the European Union, the European Medicines Agency's (EMA's) European Public Assessment Report (EPAR) is an important source of information for healthcare professionals and patients that allows them to understand important risks and uncertainti...

Methodology for Good Machine Learning with Multi-Omics Data.

Clinical pharmacology and therapeutics
In 2020, Novartis Pharmaceuticals Corporation and the U.S. Food and Drug Administration (FDA) started a 4-year scientific collaboration to approach complex new data modalities and advanced analytics. The scientific question was to find novel radio-ge...

Applications of Advanced Natural Language Processing for Clinical Pharmacology.

Clinical pharmacology and therapeutics
Natural language processing (NLP) is a branch of artificial intelligence, which combines computational linguistics, machine learning, and deep learning models to process human language. Although there is a surge in NLP usage across various industries...

Machine Learning in Modeling Disease Trajectory and Treatment Outcomes: An Emerging Enabler for Model-Informed Precision Medicine.

Clinical pharmacology and therapeutics
The increasing breadth and depth of resolution in biological and clinical data, including -omics and real-world data, requires advanced analytical techniques like artificial intelligence (AI) and machine learning (ML) to fully appreciate the impact o...

Using Machine Learning to Individualize Treatment Effect Estimation: Challenges and Opportunities.

Clinical pharmacology and therapeutics
The use of data from randomized clinical trials to justify treatment decisions for real-world patients is the current state of the art. It relies on the assumption that average treatment effects from the trial can be extrapolated to patients with per...

Current Status and Future Directions: The Application of Artificial Intelligence/Machine Learning for Precision Medicine.

Clinical pharmacology and therapeutics
Technological innovations, such as artificial intelligence (AI) and machine learning (ML), have the potential to expedite the goal of precision medicine, especially when combined with increased capacity for voluminous data from multiple sources and e...

Measurement and Mitigation of Bias in Artificial Intelligence: A Narrative Literature Review for Regulatory Science.

Clinical pharmacology and therapeutics
Artificial intelligence (AI) is increasingly being used in decision making across various industries, including the public health arena. Bias in any decision-making process can significantly skew outcomes, and AI systems have been shown to exhibit bi...

Artificial Intelligence: From Buzzword to Useful Tool in Clinical Pharmacology.

Clinical pharmacology and therapeutics
The advent of artificial intelligence (AI) in clinical pharmacology and drug development is akin to the dawning of a new era. Previously dismissed as merely technological hype, these approaches have emerged as promising tools in different domains, in...