Cytometry. Part A : the journal of the International Society for Analytical Cytology
Aug 15, 2022
Recent studies have suggested that circulating tumor cells with abnormalities in gene copy numbers in mononuclear cell-enriched peripheral blood samples, such as circulating genetically abnormal cells (CACs), can be used as a non-invasive tool to det...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Jun 29, 2022
Intelligent image-activated cell sorting (iIACS) has enabled high-throughput image-based sorting of single cells with artificial intelligence (AI) algorithms. This AI-on-a-chip technology combines fluorescence microscopy, AI-based image processing, s...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 7, 2022
Increasingly, highly multiplexed tissue imaging methods are used to profile protein expression at the single-cell level. However, a critical limitation is the lack of robust cell segmentation tools for tissue sections. We present Multiplexed Image Re...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Jan 21, 2022
Automated cell segmentation is key for rapid and accurate investigation of cell responses. As instrumentation resolving power increases, clear delineation of newly revealed cellular features at the submicron through nanoscale becomes important. Relia...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Jun 19, 2021
The measurement of cell viability plays an essential role in the area of cell biology. At present, the common methods for cell viability assay mainly on the responses of cells to different dyes. However, the additional steps of cell staining will con...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
May 7, 2021
The Coulter principle is a widespread technique for sizing red blood cells (RBCs) in hematological analyzers. It is based on the monitoring of the electrical perturbations generated by cells passing through a micro-orifice, in which a concentrated el...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 20, 2021
Imaging flow cytometry has become a popular technology for bioparticle image analysis because of its capability of capturing thousands of images per second. Nevertheless, the vast number of images generated by imaging flow cytometry imposes great cha...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 20, 2021
Urine cytology is a test for the detection of high-grade bladder cancer. In clinical practice, the pathologist would manually scan the sample under the microscope to locate atypical and malignant cells. They would assess the morphology of these cells...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 17, 2021
Structured illumination microscopy (SIM) is widely used in biological imaging for its high resolution, fast imaging speed, and simple optical setup. However, when imaging thick samples, the structured illumination patterns in SIM will suffer from opt...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Dec 13, 2020
To understand the physiology and pathology of disease, capturing the heterogeneity of cell types within their tissue environment is fundamental. In such an endeavor, the human kidney presents a formidable challenge because its complex organizational ...