An important limitation of state-of-the-art deep learning networks is that they do not recognize when their input is dissimilar to the data on which they were trained and proceed to produce outputs that will be unreliable or nonsensical. In this work...
Recently deep neural networks, which require a large amount of annotated samples, have been widely applied in nuclei instance segmentation of H&E stained pathology images. However, it is inefficient and unnecessary to label all pixels for a dataset o...
Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifacts, denoising is largely studied both within the medical imaging community and beyond the community as a gener...
Lowering the radiation dose in computed tomography (CT) can greatly reduce the potential risk to public health. However, the reconstructed images from dose-reduced CT or low-dose CT (LDCT) suffer from severe noise which compromises the subsequent dia...
Image registration is a fundamental medical image analysis task, and a wide variety of approaches have been proposed. However, only a few studies have comprehensively compared medical image registration approaches on a wide range of clinically releva...
Registration of dynamic CT image sequences is a crucial preprocessing step for clinical evaluation of multiple physiological determinants in the heart such as global and regional myocardial perfusion. In this work, we present a deformable deep learni...
Deep learning-based semi-supervised learning (SSL) algorithms are promising in reducing the cost of manual annotation of clinicians by using unlabelled data, when developing medical image segmentation tools. However, to date, most existing semi-super...
Anatomical segmentation is a fundamental task in medical image computing, generally tackled with fully convolutional neural networks which produce dense segmentation masks. These models are often trained with loss functions such as cross-entropy or D...
Non-rigid registration between 3D surfaces is an important but notorious problem in medical imaging, because finding correspondences between non-isometric instances is mathematically non-trivial. We propose a novel self-supervised method to learn sha...
Deep neural networks have shown promise in image reconstruction tasks, although often on the premise of large amounts of training data. In this paper, we present a new approach to exploit the geometry and physics underlying electrocardiographic imagi...
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