Journal of computational biology : a journal of computational molecular cell biology
Sep 13, 2023
In the field of drug development and repositioning, the prediction of drug-disease associations is a critical task. A recently proposed method for predicting drug-disease associations based on graph convolution relies heavily on the features of adjac...
Journal of computational biology : a journal of computational molecular cell biology
Aug 16, 2023
Spiking neural network (SNN) simulators play an important role in neural system modeling and brain function research. They can help scientists reproduce and explore neuronal activities in brain regions, neuroscience, brain-like computing, and other f...
Journal of computational biology : a journal of computational molecular cell biology
Jul 31, 2023
International Classification of Diseases (ICD) serves as the foundation for generating comparable global disease statistics across regions and over time. The process of ICD coding involves assigning codes to diseases based on clinical notes, which ca...
Journal of computational biology : a journal of computational molecular cell biology
Oct 14, 2022
Single-cell multi-omics technologies enable comprehensive interrogation of cellular regulation, yet most single-cell assays measure only one type of activity-such as transcription, chromatin accessibility, DNA methylation, or 3D chromatin architectur...
Journal of computational biology : a journal of computational molecular cell biology
Sep 1, 2022
Species tree estimation is frequently based on phylogenomic approaches that use multiple genes from throughout the genome. However, for a combination of reasons (ranging from sampling biases to more biological causes, as in gene birth and loss), gene...
Journal of computational biology : a journal of computational molecular cell biology
Aug 18, 2022
Journal of computational biology : a journal of computational molecular cell biology
Aug 18, 2022
The detection and classification of nuclei play an important role in the histopathological analysis. It aims to find out the distribution of nuclei in the histopathology images for the next step of analysis and research. However, it is very challengi...
Journal of computational biology : a journal of computational molecular cell biology
Aug 16, 2022
Molecule generation is the procedure to generate initial novel molecule proposals for molecule design. Molecules are first projected into continuous vectors in chemical latent space, and then, these embedding vectors are decoded into molecules under ...
Journal of computational biology : a journal of computational molecular cell biology
Aug 10, 2022
The scientific community is rapidly generating protein sequence information, but only a fraction of these proteins can be experimentally characterized. While promising deep learning approaches for protein prediction tasks have emerged, they have comp...
Journal of computational biology : a journal of computational molecular cell biology
Jun 24, 2022
Coordinated hunting is widely observed in animals, and sharing rewards is often considered a major incentive for its success. While current theories about the role played by sharing in coordinated hunting are based on correlational evidence, we revea...