Journal of controlled release : official journal of the Controlled Release Society
Jun 15, 2023
Sustained local delivery of meloxicam by polymeric structures is desirable for preventing subacute inflammation and biofilm formation following tissue incision or injury. Our previous study demonstrated that meloxicam release from hot-melt extruded (...
Journal of controlled release : official journal of the Controlled Release Society
Jan 19, 2023
Chemotherapy is still the most effective technique to treat many forms of cancer. However, it also carries a high risk of side effects. Numerous nanomedicines have been developed to avoid unintended consequences and significant negative effects of co...
Journal of controlled release : official journal of the Controlled Release Society
Dec 7, 2022
The newly-emerged pathological conditions and increased rates of drug resistance necessitate application of the state-of-the-art technologies for accelerated discovery of the therapeutic candidates and obtaining comprehensive knowledge about their ta...
Journal of controlled release : official journal of the Controlled Release Society
Nov 16, 2022
In this review, we describe the current status and challenges in applying machine-learning techniques to the analysis and prediction of pharmacokinetic data. The theory of pharmacokinetics has been developed over decades on the basis of physiology an...
Journal of controlled release : official journal of the Controlled Release Society
Nov 11, 2022
This perspective article draws a distinction between some of the well-known drug classification systems and a "Chemistry Classification System" (CCS). Rather than have drug classification based on some simple properties like solubility and permeabili...
Journal of controlled release : official journal of the Controlled Release Society
Jul 8, 2022
Manipulation and targeted navigation of nanobots in complex biological conditions can be achieved by chemical reactions, by applying external forces, and via motile cells. Several studies have applied fuel-based and fuel-free propulsion mechanisms fo...
Journal of controlled release : official journal of the Controlled Release Society
Aug 19, 2021
In recent decades pharmaceutics and drug delivery have become increasingly critical in the pharmaceutical industry due to longer time, higher cost, and less productivity of new molecular entities (NMEs). However, current formulation development still...
Journal of controlled release : official journal of the Controlled Release Society
Jul 30, 2021
Three-dimensional printing (3DP) is a transformative technology that is advancing pharmaceutical research by producing personalized drug products. However, advances made via 3DP have been slow due to the lengthy trial-and-error approach in optimizati...
Journal of controlled release : official journal of the Controlled Release Society
Jul 8, 2017
The advancements in electronics and the progress in nanotechnology have resulted in path breaking development that will transform the way diagnosis and treatment are carried out currently. This development is Medical Capsule Robots, which has emerged...