Atrial fibrillation (AF), the most common form of cardiac arrhythmia, is closely associated with atrial fibrosis and electrophysiological remodeling, both of which contribute to its persistence and recurrence. Current treatment strategies remain limi...
International journal of pharmaceutics
Nov 4, 2025
Liposomes have transformed drug delivery by enhancing the solubility, stability, and bioavailability of therapeutic agents, driving widespread clinical adoption and contributing to a rapidly expanding multi-billion-dollar market. However, despite the...
Nanoparticle-based therapies have gained attention in recent years as promising treatments for rheumatoid arthritis (RA), due to the potential offered for targeted delivery, controlled drug release, and improved biocompatibility. A deep understanding...
Microfluidic technologies have revolutionized the synthesis of nanocarriers for drug and gene delivery, providing unparalleled precision and efficiency in the production of therapeutic nanoparticles. This review highlights recent advancements in micr...
Colorectal cancer (CRC) remains a major global health burden, necessitating more effective and selective therapeutic approaches. Nanocarrier-based drug delivery systems offer significant advantages by enhancing drug accumulation in tumors, reducing o...
Cancer remains one of the most significant global health challenges, with its burden continuing to rise. The limitations of conventional anticancer therapies caused by the lack of tissue selectivity, demands urgent development of safer and more selec...
Chemical communications (Cambridge, England)
Aug 28, 2025
There is a growing interest in developing one-health "plug and play" platforms for making different therapeutics/prophylactics to target various biological entities such as viruses, cancer cells, or bacteria. Such a platform could benefit from advanc...
This work presents a comprehensive study on the prediction of phenytoin solubility at supercritical state using advanced techniques including machine learning analysis. The solubility of small-molecule pharmaceutical was analyzed and calculated to en...
International journal of pharmaceutics
Aug 19, 2025
Nanoparticles (NPs) represent critical roles both for drug delivery systems and diagnostics. Nevertheless, due to interaction in a biological medium and specific consequences-like formation of protein corona (PC), changes may happen that have influen...
Journal of controlled release : official journal of the Controlled Release Society
Aug 18, 2025
Nano-sized drug delivery systems have emerged as a more effective, versatile means for improving cancer treatment. However, the complexity of drug delivery to cancer involves intricate interactions between physiological and physicochemical processes ...
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