Identification of drug-target interactions (DTI) is a central task in drug discovery processes. In this work, a simple but effective regularized least squares integrating with nonlinear kernel fusion (RLS-KF) algorithm is proposed to perform DTI pred...
Surveying threatened and invasive species to obtain accurate population estimates is an important but challenging task that requires a considerable investment in time and resources. Estimates using existing ground-based monitoring techniques, such as...
BACKGROUND: Natural language processing (NLP) applications are increasingly important in biomedical data analysis, knowledge engineering, and decision support. Concept recognition is an important component task for NLP pipelines, and can be either ge...
Quality assessment of a protein model is to predict the absolute or relative quality of a protein model using computational methods before the native structure is available. Single-model methods only need one model as input and can predict the absolu...
Computational intelligence and neuroscience
Jan 14, 2016
An improved teaching-learning-based optimization with combining of the social character of PSO (TLBO-PSO), which is considering the teacher's behavior influence on the students and the mean grade of the class, is proposed in the paper to find the glo...
Computational intelligence and neuroscience
Jan 14, 2016
Color quantization is an essential technique in color image processing, which has been continuously researched. It is often used, in particular, as preprocessing for many applications. Self-Organizing Map (SOM) color quantization is one of the most e...
Neural networks : the official journal of the International Neural Network Society
Jan 13, 2016
Echo State Networks are efficient time-series predictors, which highly depend on the value of the spectral radius of the reservoir connectivity matrix. Based on recent results on the mean field theory of driven random recurrent neural networks, enabl...
UNLABELLED: Most patient care questions raised by clinicians can be answered by online clinical knowledge resources. However, important barriers still challenge the use of these resources at the point of care.
Environmental and molecular mutagenesis
Jan 13, 2016
Several endpoints associated with cellular responses to DNA damage as well as overt cytotoxicity were multiplexed into a miniaturized, "add and read" type flow cytometric assay. Reagents included a detergent to liberate nuclei, RNase and propidium io...
Computer methods and programs in biomedicine
Jan 12, 2016
Automatic classification of sleep stages is one of the most important methods used for diagnostic procedures in psychiatry and neurology. This method, which has been developed by sleep specialists, is a time-consuming and difficult process. Generally...
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