AIMC Topic: Amino Acid Sequence

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Crystallization and X-ray diffraction of an ectoine hydroxylase from Bacillus pseudofirmus OF4.

Wei sheng wu xue bao = Acta microbiologica Sinica Nov 4, 2015
OBJECTIVE: To study crystallization and X-Ray diffraction of ectoine hydroxylase from Bacillus pseudofirmus OF4.
Amino Acids, Diamino Bacterial Proteins Mixed Function Oxygenases Amino Acid Sequence Bacillus Sequence Alignment Crystallization X-Ray Diffraction Molecular Sequence Data
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[Alkaline-adapted beta-mannanase of Bacillus pumilus: gene heterologous expression and enzyme characterization].

Wei sheng wu xue bao = Acta microbiologica Sinica Nov 4, 2015
OBJECTIVE: We expressed a novel alkaline-adapted beta-mannanase gene and characterized the enzyme for potential industrial applications.
Enzyme Stability Base Sequence Bacillus Molecular Sequence Data Kinetics Amino Acid Sequence Cloning, Molecular Phylogeny Escherichia coli beta-Mannosidase Sequence Alignment Alkalies Gene Expression Bacterial Proteins
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AVP-IC50 Pred: Multiple machine learning techniques-based prediction of peptide antiviral activity in terms of half maximal inhibitory concentration (IC50).

Biopolymers Nov 1, 2015
Peptide-based antiviral therapeutics has gradually paved their way into mainstream drug discovery research. Experimental determination of peptides' antiviral activity as expressed by their IC50 values involves a lot of effort. Therefore, we have deve...
Machine Learning Internet Amino Acid Sequence Algorithms Inhibitory Concentration 50 Peptides Molecular Sequence Data Antiviral Agents
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Predicting Protein-Protein Interaction Sites with a Novel Membership Based Fuzzy SVM Classifier.

IEEE/ACM transactions on computational biology and bioinformatics Jan 1, 2015
Predicting residues that participate in protein-protein interactions (PPI) helps to identify, which amino acids are located at the interface. In this paper, we show that the performance of the classical support vector machine (SVM) algorithm can furt...
Molecular Sequence Data Sequence Alignment Sequence Analysis, Protein Algorithms Pattern Recognition, Automated Computer Simulation Binding Sites Protein Binding Protein Interaction Mapping Humans Fuzzy Logic Models, Chemical Models, Statistical Amino Acid Sequence
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Sequence based human leukocyte antigen gene prediction using informative physicochemical properties.

International journal of data mining and bioinformatics Jan 1, 2015
Prediction of different classes within the human leukocyte antigen (HLA) gene family can provide insight into the human immune system and its response to viral pathogens. Therefore, it is desirable to develop an efficient and easily interpretable met...
Sequence Analysis, Protein Humans Data Mining HLA-A Antigens Structure-Activity Relationship Pattern Recognition, Automated Support Vector Machine Algorithms Leukocytes Molecular Sequence Data Databases, Protein Amino Acid Sequence
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Exploiting multi-layered vector spaces for signal peptide detection.

International journal of data mining and bioinformatics Jan 1, 2015
Analysing and classifying sequences based on similarities and differences is a mathematical problem of escalating relevance and importance in many scientific disciplines. One of the primary challenges in applying machine learning algorithms to sequen...
Algorithms Databases, Protein Amino Acid Sequence Peptides Support Vector Machine Data Mining Sequence Alignment Protein Sorting Signals Pattern Recognition, Automated Sequence Analysis, Protein Molecular Sequence Data
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A novel fractal approach for predicting G-protein-coupled receptors and their subfamilies with support vector machines.

Bio-medical materials and engineering Jan 1, 2015
G-protein-coupled receptors (GPCRs) are seven membrane-spanning proteins and regulate many important physiological processes, such as vision, neurotransmission, immune response and so on. GPCRs-related pathways are the targets of a large number of ma...
Fractals Molecular Sequence Data Sequence Alignment Sequence Analysis, Protein Support Vector Machine Databases, Protein Algorithms Receptors, G-Protein-Coupled Data Mining Pattern Recognition, Automated Structure-Activity Relationship Amino Acid Sequence
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Sequence-based protein superfamily classification using computational intelligence techniques: a review.

International journal of data mining and bioinformatics Jan 1, 2015
Protein superfamily classification deals with the problem of predicting the family membership of newly discovered amino acid sequence. Although many trivial alignment methods are already developed by previous researchers, but the present trend demand...
Computational Biology Proteins Amino Acid Sequence Sequence Analysis, Protein Artificial Intelligence Algorithms
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Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.

Methods in molecular biology (Clifton, N.J.) Jan 1, 2015
Cell-penetrating peptides (CPPs) have proven their potential as versatile drug delivery vehicles. Last decade has witnessed an unprecedented growth in CPP-based research, demonstrating the potential of CPPs as therapeutic candidates. In the past, man...
Drug Carriers Proteins Amino Acid Sequence Cell-Penetrating Peptides Animals Computer-Aided Design Support Vector Machine Molecular Sequence Data Amino Acid Motifs Machine Learning Computer Simulation Humans
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Artificial neural networks for dihedral angles prediction in enzyme loops: a novel approach.

International journal of bioinformatics research and applications Jan 1, 2015
Structure prediction of proteins is considered a limiting step and determining factor in drug development and in the introduction of new therapies. Since the 3D structures of proteins determine their functionalities, prediction of dihedral angles rem...
Computer Simulation Models, Molecular Models, Chemical Amino Acid Sequence Neural Networks, Computer Pattern Recognition, Automated Sequence Analysis, Protein Protein Structure, Tertiary Protein Conformation Enzymes Molecular Sequence Data
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