AIMC Topic: Analytic Sample Preparation Methods

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Recent advances in robotic protein sample preparation for clinical analysis and other biomedical applications.

Clinica chimica acta; international journal of clinical chemistry Apr 17, 2020
Discovery of new protein biomarker candidates has become a major research goal in the areas of clinical chemistry, analytical chemistry, and biomedicine. These important species constitute the molecular target when it comes to diagnosis, prognosis, a...
Humans Proteins Robotics Chemistry Techniques, Analytical Analytic Sample Preparation Methods
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Magnetic nanoparticles coated with poly(p-phenylenediamine-co-thiophene) as a sorbent for preconcentration of organophosphorus pesticides.

Mikrochimica acta Dec 5, 2017
The authors describe the preparation of FeO nanoparticles coated with poly(p-phenylenediamine-co-thiophene). The resulting nanoparticles (NPs) are shown to be viable sorbents for use in magnetic solid-phase extraction (MSPE) of organophosphorus pesti...
Adsorption Magnetite Nanoparticles Nanocomposites Fruit and Vegetable Juices Pesticides Organophosphorus Compounds Chromatography, Gas Thiophenes Analytic Sample Preparation Methods Phenylenediamines Polymerization
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Large volume preconcentration and determination of nanomolar concentrations of iron in seawater using a renewable cellulose 8-hydroquinoline sorbent microcolumn and universal approach of post-column eluate utilization in a Lab-on-Valve system.

Talanta Dec 18, 2015
We report on a Lab-On-Valve (LOV) configuration for analyte preconcentration from milliliter sample volumes using confluent mixing in the holding coil for in-line addition of loading buffer. The system was applied to the spectrophotometric determinat...
Reproducibility of Results Cellulose Limit of Detection Color Iron Hydrogen-Ion Concentration Solid Phase Extraction Buffers Seawater Analytic Sample Preparation Methods Chelating Agents Phenanthrolines Oxyquinoline
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The application of fuzzy statistics and linear discriminant analysis as criteria for optimizing the preparation of plasma for matrix-assisted laser desorption/ionization mass spectrometry peptide profiling.

Clinica chimica acta; international journal of clinical chemistry Jul 9, 2015
An alternative bioinformatics approach based on fuzzy theory statistics and linear discriminant analysis is proposed for the interpretation of MALDI MS spectra in peptide profiling. When applied, the methodology enables the establishment of a reprodu...
Humans Pregnancy Female Young Adult Adult Computational Biology Fuzzy Logic Discriminant Analysis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Diabetes, Gestational Analytic Sample Preparation Methods
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