AIMC Topic: Phenylenediamines

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CDKN1A and EGR1 are key genes for endoplasmic reticulum stress-induced ferroptosis in MASH.

Free radical biology & medicine May 23, 2025
Metabolic dysfunction-associated steatohepatitis (MASH) is a complex liver disease whose pathogenesis involving endoplasmic reticulum (ER) stress and ferroptosis. However, key regulatory genes remain poorly understood, hindering the development of ef...
Humans Animals Ferroptosis Non-alcoholic Fatty Liver Disease Liver Diet, High-Fat Phenylenediamines Early Growth Response Protein 1 Gene Expression Regulation Endoplasmic Reticulum Stress Disease Models, Animal Hep G2 Cells Cyclin-Dependent Kinase Inhibitor p21 Mice, Inbred C57BL Mice Fatty Liver Male
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Prediction of p-phenylenediamine antioxidant concentrations in human urine using machine learning models.

Journal of hazardous materials Jan 10, 2025
p-phenylenediamine antioxidants (PPDs) are extensively used in rubber manufacturing for their potent antioxidative properties, but PPDs and 2-anilino-5-[(4-methylpentan-2yl)amino]cyclohexa-2,5-diene-1,4-dione (6PPDQ) pose potential environmental and ...
Antioxidants Environmental Pollutants Adolescent Environmental Exposure Phenylenediamines Adult Male Middle Aged China Aged Young Adult Female Humans Machine Learning
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Mass Spectrometry Probe Combined with Machine Learning to Capture the Relationship between Metabolites and Mitochondrial Complex Activity at the Whole-Cell Level.

Analytical chemistry Nov 1, 2024
Mitochondrial complex activity controls a multitude of physiological processes by regulating the cellular metabolism. Current methods for evaluating mitochondrial complex activity mainly focus on single metabolic reactions within mitochondria. These ...
Humans Tandem Mass Spectrometry Phenylenediamines Animals Machine Learning Mitochondria
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Predicting malnutrition in gastric cancer patients using computed tomography(CT) deep learning features and clinical data.

Clinical nutrition (Edinburgh, Scotland) Feb 6, 2024
OBJECTIVE: The aim of this study is using clinical factors and non-enhanced computed tomography (CT) deep features of the psoas muscles at third lumbar vertebral (L3) level to construct a model to predict malnutrition in gastric cancer before surgery...
Phenylenediamines Benzamides Tomography Malnutrition Albumins Deep Learning Humans Retrospective Studies Stomach Neoplasms
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Magnetic nanoparticles coated with poly(p-phenylenediamine-co-thiophene) as a sorbent for preconcentration of organophosphorus pesticides.

Mikrochimica acta Dec 5, 2017
The authors describe the preparation of FeO nanoparticles coated with poly(p-phenylenediamine-co-thiophene). The resulting nanoparticles (NPs) are shown to be viable sorbents for use in magnetic solid-phase extraction (MSPE) of organophosphorus pesti...
Analytic Sample Preparation Methods Phenylenediamines Thiophenes Fruit and Vegetable Juices Magnetite Nanoparticles Polymerization Adsorption Organophosphorus Compounds Pesticides Nanocomposites Chromatography, Gas
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