Artificial Intelligence Medical Compendium
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Angiopoietin-Like Protein 4
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Transcriptome-wide analysis reveals potential roles of CFD and ANGPTL4 in fibroblasts regulating B cell lineage for extracellular matrix-driven clustering and novel avenues for immunotherapy in breast cancer.
Molecular medicine (Cambridge, Mass.)
40340806
BACKGROUND: The remodeling of the extracellular matrix (ECM) plays a pivotal role in tumor progression and drug resistance. However, the compositional patterns of ECM in breast cancer and their underlying biological functions remain elusive.
Angiopoietin-Like Protein 4
B-Lymphocytes
Breast Neoplasms
Cell Lineage
Extracellular Matrix
Female
Fibroblasts
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Gene Regulatory Networks
Humans
Immunotherapy
Prognosis
Transcriptome
Tumor Microenvironment
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