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Arabidopsis

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Comparison of machine learning methods for genomic prediction of selected Arabidopsis thaliana traits.

PloS one
We present a comparison of machine learning methods for the prediction of four quantitative traits in Arabidopsis thaliana. High prediction accuracies were achieved on individuals grown under standardized laboratory conditions from the 1001 Arabidops...

HNCGAT: a method for predicting plant metabolite-protein interaction using heterogeneous neighbor contrastive graph attention network.

Briefings in bioinformatics
The prediction of metabolite-protein interactions (MPIs) plays an important role in plant basic life functions. Compared with the traditional experimental methods and the high-throughput genomics methods using statistical correlation, applying hetero...

AtML: An Arabidopsis thaliana root cell identity recognition tool for medicinal ingredient accumulation.

Methods (San Diego, Calif.)
Arabidopsis thaliana synthesizes various medicinal compounds, and serves as a model plant for medicinal plant research. Single-cell transcriptomics technologies are essential for understanding the developmental trajectory of plant roots, facilitating...

Machine learning-based identification of general transcriptional predictors for plant disease.

The New phytologist
This study investigated the generalizability of Arabidopsis thaliana immune responses across diverse pathogens, including Botrytis cinerea, Sclerotinia sclerotiorum, and Pseudomonas syringae, using a data-driven, machine learning approach. Machine le...

Deep learning-based cytoskeleton segmentation for accurate high-throughput measurement of cytoskeleton density.

Protoplasma
Microscopic analyses of cytoskeleton organization are crucial for understanding various cellular activities, including cell proliferation and environmental responses in plants. Traditionally, assessments of cytoskeleton dynamics have been qualitative...

Enhancing Arabidopsis thaliana ubiquitination site prediction through knowledge distillation and natural language processing.

Methods (San Diego, Calif.)
Protein ubiquitination is a critical post-translational modification (PTM) involved in diverse biological processes and plays a pivotal role in regulating physiological mechanisms and disease states. Despite various efforts to develop ubiquitination ...

Lessons from Deep Learning Structural Prediction of Multistate Multidomain Proteins-The Case Study of Coiled-Coil NOD-like Receptors.

International journal of molecular sciences
We test here the prediction capabilities of the new generation of deep learning predictors in the more challenging situation of multistate multidomain proteins by using as a case study a coiled-coil family of Nucleotide-binding Oligomerization Domain...

Deep Learning Enhances Precision of Citrullination Identification in Human and Plant Tissue Proteomes.

Molecular & cellular proteomics : MCP
Citrullination is a critical yet understudied post-translational modification (PTM) implicated in various biological processes. Exploring its role in health and disease requires a comprehensive understanding of the prevalence of this PTM at a proteom...

An NLP-based method to mine gene and function relationships from published articles.

Scientific reports
Understanding the intricacies of genes function within biological systems is paramount for scientific advancement and medical progress. Owing to the evolving landscape of this research and the complexity of biological processes, however, this task pr...

AtSubP-2.0: An integrated web server for the annotation of Arabidopsis proteome subcellular localization using deep learning.

The plant genome
The organization of subcellular components in a cell is critical for its function and studying cellular processes, protein-protein interactions, identifying potential drug targets, network analysis, and other systems biology mechanisms. Determining p...