Proceedings of the National Academy of Sciences of the United States of America
Dec 10, 2025
DNA methylation is a conserved epigenetic modification essential for maintaining genome stability. However, how methyltransferases maintain CG methylation within compact chromatin, including centromeres, remains unclear. In humans, CDCA7 is necessary...
BACKGROUND: Splice site prediction in plant genomes poses substantial challenges that can be addressed using deep learning models. U2-type introns are especially useful for such studies given their ubiquity in plant genomes and the availability of ri...
BACKGROUND: Plants are always exposed to a variety of stressful environments, including heat and drought stress, which severely impact the growth, development, and productivity of the plants. To overcome such challenges, plants have evolved diverse a...
Stomata are vital for controlling gas exchange and water vapor release, which significantly affect photosynthesis and transpiration. Characterizing stomatal traits such as size, density, and distribution is essential for adaptation to the environment...
Phytopathogens secrete effector molecules to manipulate host immunity and metabolism. Recent advances in structural genomics have identified fungal effector families whose members adopt similar folds despite sequence divergence, highlighting their im...
Infrared thermal imaging offers a rapid and sensitive approach to assessing temperature changes in plants caused by salt stress, even in the early stages of exposure. Given the increasing prevalence of salt contamination in the environment, it is ess...
The circadian clock of plants contributes to their survival and fitness. However, understanding clock function at the transcriptome level and its response to the environment requires assaying across high resolution time-course experiments. Generating...
Multiple C2 Domains and Transmembrane region Proteins (MCTPs) in plants have been identified as important functional and structural components of plasmodesmata cytoplasmic bridges, which are vital for cell-cell communication. MCTPs are endoplasmic re...
Proteins are the molecular machines of life with numerous applications in energy, health, and sustainability. However, engineering proteins with desired functions for practical applications remains slow, expensive, and specialist-dependent. Here we r...
In Arabidopsis, exposure to microbial volatile compounds promotes thiol reduction of the Cys95 residue of the photosynthetic enzyme fructose-1,6-bisphosphatase (cFBP1). Although highly conserved in plants, the Cys95 function still remains unknown. We...
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