Restless legs syndrome (RLS) is a relatively common neurosensory disorder that causes an irresistible urge for leg movement. RLS causes sleep disturbances and reduced quality of life, but accurate diagnosis remains challenging owing to the reliance o...
Heart failure (HF) encompasses a diverse clinical spectrum, including instances of transient HF or HF with recovered ejection fraction, alongside persistent cases. This dynamic condition exhibits a growing prevalence and entails substantial healthcar...
Melanoma is a highly malignant skin tumor with poor prognosis. Circadian rhythm is closely related to melanoma pathogenesis. This study aimed to identify key circadian rhythm genes (CRGs) in melanoma and explore their potential as diagnostic and prog...
OBJECTIVE: This study aimed to identify key clock genes closely associated with major depressive disorder (MDD) using bioinformatics and machine learning approaches.
Most organisms synchronize to an approximately 24-hour (circadian) rhythm. This study introduces a novel deep learning-powered video tracking method to assess the stability, fragmentation, robustness and synchronization of activity rhythms in . Exper...
Proceedings of the National Academy of Sciences of the United States of America
39269777
is an important cyanobacterium that serves as a versatile and robust model for studying circadian biology and photosynthetic metabolism. Its transcriptional regulatory network (TRN) is of fundamental interest, as it orchestrates the cell's adaptatio...
Medical science monitor : international medical journal of experimental and clinical research
39623707
BACKGROUND Predicting 24-hour intraocular pressure (IOP) fluctuations is crucial for enhancing glaucoma management. Traditional methods of measuring 24-hour IOP fluctuations are complex and present certain limitations. The present study leverages mac...
The accurate classification of menstrual cycle phases and detection of ovulation is critical for women's health management, particularly in addressing infertility, alleviating premenstrual syndrome, and preventing hormone-related disorders. However, ...
Circadian rhythms, which are the natural cycles that dictate various physiological processes over a 24-h period, have been increasingly recognized as important in the management and treatment of various human diseases. However, the lack of sufficient...
Major depressive disorder (MDD) is associated with reduced heart rate variability (HRV), but its link to circadian rhythm modulation (CRM) of HRV is unclear. Given that depression disrupts circadian rhythms, assessing HRV fluctuations may better capt...