AIMC Topic: Arachidonate 5-Lipoxygenase

Clear Filters Showing 1 to 4 of 4 articles

Specialized oxygenated heterocyclics from Villorita cyprinoides with cyclooxygenase-2 and 5-lipoxygenase inhibitory properties.

Food research international (Ottawa, Ont.) Dec 28, 2017
Villorita cyprinoides is traditional seafood in the coastal regions of Arabian Sea. Bioactivity-guided purification of ethyl acetate:methanol extract of V. cyprinoides resulted in the identification of two O-spirocyclic ether derivatives (1-2) along ...
Oxygen Lipoxygenase Bivalvia Cyclooxygenase 2 Lipoxygenase Inhibitors Molecular Structure Animals Arachidonate 5-Lipoxygenase Seafood Molecular Docking Simulation Structure-Activity Relationship Antioxidants Humans Biological Products Cyclooxygenase 2 Inhibitors
View on PubMed DOI

Synthesis of new analogs of AKBA and evaluation of their anti-inflammatory activities.

Bioorganic & medicinal chemistry Dec 29, 2016
A new series of 11-keto-β-boswellic acid and 3-O-acetyl-11-keto-β-boswellic acid analogs (5, 7, 8, 10, 13, 18a-d, 27a-c, 28a-d) were synthesized by modification of hydroxyl and acid functional moieties of boswellic acids. The structures of these anal...
Humans Structure-Activity Relationship Dose-Response Relationship, Drug Lipoxygenase Inhibitors Arachidonate 5-Lipoxygenase Molecular Structure Triterpenes Anti-Inflammatory Agents, Non-Steroidal
View on PubMed DOI

The study of dual COX-2/5-LOX inhibitors by using electronic-topological approach based on data on the ligand-receptor interactions.

Journal of molecular graphics & modelling Jun 19, 2015
Structural and electronic factors influencing selective inhibition of cyclooxygenase-2 and 5-lipoxygenase (COX-2/5-LOX) were studied by using Electronic-Topological Method combined with Neural Networks (ETM-NN), molecular docking, and Density Functio...
Neural Networks, Computer Algorithms Humans Datasets as Topic Catalytic Domain Cyclooxygenase 2 Inhibitors Lipoxygenase Inhibitors Substrate Specificity Cyclooxygenase 2 Arachidonate 5-Lipoxygenase Protein Binding Molecular Structure Structure-Activity Relationship Molecular Docking Simulation Quantum Theory Ligands
View on PubMed DOI

[Mechanism of Musk and Borneol on Inflammatory of Cerebral Ischemia and Reperfusion Injury at Different Time Points of Acute Phase in Rats].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials Oct 1, 2015
OBJECTIVE: To investigate the mechanism of Musk and Borneol on cerebral ischemia and reperfusion injury at different time points of acute phase in rats.
Fatty Acids, Monounsaturated Camphanes Cyclooxygenase 2 Anti-Inflammatory Agents Arachidonate 5-Lipoxygenase Brain Ischemia Rats, Sprague-Dawley Reperfusion Injury Rats Animals Brain
View on PubMed
Popular Topics
Recent Journals