AIMC Topic: Bacteria

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Machine learning approach identifies prominent codons from different degenerate groups influencing gene expression in bacteria.

Genes to cells : devoted to molecular & cellular mechanisms
Unequal usage of synonymous codons is known as codon usage bias (CUB), which is generally different between the high-expression genes (HEG) and low-expression genes (LEG) in organisms is not yet adequately reported across different bacteria. In this ...

Research on soft sensing method of photosynthetic bacteria fermentation process based on ant colony algorithm and least squares support vector machine.

Preparative biochemistry & biotechnology
Photosynthetic bacteria wastewater treatment is an efficient water pollution treatment method, but photosynthetic bacteria fermentation is a multivariable, non-linear, and time-varying process. So it is difficult to establish an accurate model. Aimin...

On-chip bacterial foraging training in silicon photonic circuits for projection-enabled nonlinear classification.

Nature communications
On-chip training remains a challenging issue for photonic devices to implement machine learning algorithms. Most demonstrations only implement inference in photonics for offline-trained neural network models. On the other hand, artificial neural netw...

SeqScreen: accurate and sensitive functional screening of pathogenic sequences via ensemble learning.

Genome biology
The COVID-19 pandemic has emphasized the importance of accurate detection of known and emerging pathogens. However, robust characterization of pathogenic sequences remains an open challenge. To address this need we developed SeqScreen, which accurate...

Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases.

Molecular cell
As part of the ongoing bacterial-phage arms race, CRISPR-Cas systems in bacteria clear invading phages whereas anti-CRISPR proteins (Acrs) in phages inhibit CRISPR defenses. Known Acrs have proven extremely diverse, complicating their identification....

Deep learning of a bacterial and archaeal universal language of life enables transfer learning and illuminates microbial dark matter.

Nature communications
The majority of microbial genomes have yet to be cultured, and most proteins identified in microbial genomes or environmental sequences cannot be functionally annotated. As a result, current computational approaches to describe microbial systems rely...

Deep Learning to Predict the Biosynthetic Gene Clusters in Bacterial Genomes.

Journal of molecular biology
Biosynthetic gene clusters (BGCs) in bacterial genomes code for important small molecules and secondary metabolites. Based on the validated BGCs and the corresponding sequences of protein family domains (Pfams), Pfam functions and clan information, w...

Soft Sensor Modeling Method Based on Improved KH-RBF Neural Network Bacteria Concentration in Marine Alkaline Protease Fermentation Process.

Applied biochemistry and biotechnology
Marine alkaline protease (MAP) fermentation is a complex multivariable, multi-coupled, and nonlinear process. Some unmeasured parameters will affect the quality of protease. Aiming at the problem that some parameters are difficult to be detected onli...

Antilogic, a new supervised machine learning software for the automatic interpretation of antibiotic susceptibility testing in clinical microbiology: proof-of-concept on three frequently isolated bacterial species.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
OBJECTIVE: Antibiotic susceptibility testing (AST) is necessary in order to adjust empirical antibiotic treatment, but the interpretation of results requires experience and knowledge. We have developed a machine learning software that is capable of r...

Collaborative Robot Precision Task in Medical Microbiology Laboratory.

Sensors (Basel, Switzerland)
This study focuses on the feasibility of collaborative robot implementation in a medical microbiology laboratory by demonstrating fine tasks using kinesthetic teaching. Fine tasks require sub-millimetre positioning accuracy. Bacterial colony picking ...