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Genome, Archaeal

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Pre_GI: a global map of ontological links between horizontally transferred genomic islands in bacterial and archaeal genomes.

Database : the journal of biological databases and curation
The Predicted Genomic Islands database (Pre_GI) is a comprehensive repository of prokaryotic genomic islands (islands, GIs) freely accessible at http://pregi.bi.up.ac.za/index.php. Pre_GI, Version 2015, catalogues 26 744 islands identified in 2407 ba...

1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life.

Nature biotechnology
We present 1,003 reference genomes that were sequenced as part of the Genomic Encyclopedia of Bacteria and Archaea (GEBA) initiative, selected to maximize sequence coverage of phylogenetic space. These genomes double the number of existing type strai...

Identification of prokaryotic promoters and their strength by integrating heterogeneous features.

Genomics
The promoter is a regulatory DNA region and important for gene transcriptional regulation. It is located near the transcription start site (TSS) upstream of the corresponding gene. In the post-genomics era, the availability of data makes it possible ...

A machine learning-based service for estimating quality of genomes using PATRIC.

BMC bioinformatics
BACKGROUND: Recent advances in high-volume sequencing technology and mining of genomes from metagenomic samples call for rapid and reliable genome quality evaluation. The current release of the PATRIC database contains over 220,000 genomes, and curre...

CRISPRidentify: identification of CRISPR arrays using machine learning approach.

Nucleic acids research
CRISPR-Cas are adaptive immune systems that degrade foreign genetic elements in archaea and bacteria. In carrying out their immune functions, CRISPR-Cas systems heavily rely on RNA components. These CRISPR (cr) RNAs are repeat-spacer units that are p...

Deep learning of a bacterial and archaeal universal language of life enables transfer learning and illuminates microbial dark matter.

Nature communications
The majority of microbial genomes have yet to be cultured, and most proteins identified in microbial genomes or environmental sequences cannot be functionally annotated. As a result, current computational approaches to describe microbial systems rely...