AIMC Topic: Bacteria
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Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants.
GigaScience
Jan 2, 2024
BACKGROUND: Phage therapy, reemerging as a promising approach to counter antimicrobial-resistant infections, relies on a comprehensive understanding of the specificity of individual phages. Yet the significant diversity within phage populations prese...
Coracle-a machine learning framework to identify bacteria associated with continuous variables.
Bioinformatics (Oxford, England)
Jan 2, 2024
SUMMARY: We present Coracle, an artificial intelligence (AI) framework that can identify associations between bacterial communities and continuous variables. Coracle uses an ensemble approach of prominent feature selection methods and machine learnin...
Prediction of Human Microbe-Drug Association based on Layer Attention Graph Convolutional Network.
Current medicinal chemistry
Jan 1, 2024
UNLABELLED: Human microbes are closely associated with a variety of complex diseases and have emerged as drug targets. Identification of microbe-related drugs is becoming a key issue in drug development and precision medicine. It can also provide gui...
Achieving pan-microbiome biological insights via the dbBact knowledge base.
Nucleic acids research
Jul 21, 2023
16S rRNA amplicon sequencing provides a relatively inexpensive culture-independent method for studying microbial communities. Although thousands of such studies have examined diverse habitats, it is difficult for researchers to use this vast trove of...
TIMER is a Siamese neural network-based framework for identifying both general and species-specific bacterial promoters.
Briefings in bioinformatics
Jul 20, 2023
BACKGROUND: Promoters are DNA regions that initiate the transcription of specific genes near the transcription start sites. In bacteria, promoters are recognized by RNA polymerases and associated sigma factors. Effective promoter recognition is essen...
Immune Activation Modulation via Magnetically Localized Bacteria Based Micro/Bio Robot (BBMBR).
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2023
Understanding tumor's microenvironment is one of the key factors in the cancer therapy. Especially, from the perspective of immunotherapy, immune desert or cold tumor is referred as significantly downregulated T cell in-filtration due to lack of immu...
Effects of chloramphenicol, povidone-iodine 1% and 5% eye drops on the colonisation of conjunctival flora in patients undergoing cataract surgery.
Ghana medical journal
Jun 1, 2023
OBJECTIVES: the aim was to compare 2 drops of either 5% chloramphenicol, 1% povidone-iodine or 5% povidone-iodine before cataract surgery on reducing the colonisation of bacterial flora in the conjunctiva.
Mechanism of assembly of type 4 filaments: everything you always wanted to know (but were afraid to ask).
Microbiology (Reading, England)
Mar 1, 2023
Type 4 filaments (T4F) are a superfamily of filamentous nanomachines - virtually ubiquitous in prokaryotes and functionally versatile - of which type 4 pili (T4P) are the defining member. T4F are polymers of type 4 pilins, assembled by conserved mult...
Prediction of Bacterial Immunogenicity by Machine Learning Methods.
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2023
Prediction of bacterial immunogens is a prerequisite for the process of vaccine development through reverse vaccinology. The application of in silico methods allows significant reduction in time and cost for the discovery of potential vaccine candida...
Construction of classification models for pathogenic bacteria based on LIBS combined with different machine learning algorithms.
Applied optics
Jul 20, 2022
Bacteria, especially foodborne pathogens, seriously threaten human life and health. Rapid discrimination techniques for foodborne pathogens are still urgently needed. At present, laser-induced breakdown spectroscopy (LIBS), combined with machine lear...
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