AIMC Topic: Biological Ontologies

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The Ontology of Biological and Clinical Statistics (OBCS) for standardized and reproducible statistical analysis.

Journal of biomedical semantics
BACKGROUND: Statistics play a critical role in biological and clinical research. However, most reports of scientific results in the published literature make it difficult for the reader to reproduce the statistical analyses performed in achieving tho...

OntoBrowser: a collaborative tool for curation of ontologies by subject matter experts.

Bioinformatics (Oxford, England)
UNLABELLED: The lack of controlled terminology and ontology usage leads to incomplete search results and poor interoperability between databases. One of the major underlying challenges of data integration is curating data to adhere to controlled term...

Knowledge Discovery from Biomedical Ontologies in Cross Domains.

PloS one
In recent years, there is an increasing demand for sharing and integration of medical data in biomedical research. In order to improve a health care system, it is required to support the integration of data by facilitating semantic interoperability s...

The Apollo Structured Vocabulary: an OWL2 ontology of phenomena in infectious disease epidemiology and population biology for use in epidemic simulation.

Journal of biomedical semantics
BACKGROUND: We developed the Apollo Structured Vocabulary (Apollo-SV)-an OWL2 ontology of phenomena in infectious disease epidemiology and population biology-as part of a project whose goal is to increase the use of epidemic simulators in public heal...

Using AberOWL for fast and scalable reasoning over BioPortal ontologies.

Journal of biomedical semantics
BACKGROUND: Reasoning over biomedical ontologies using their OWL semantics has traditionally been a challenging task due to the high theoretical complexity of OWL-based automated reasoning. As a consequence, ontology repositories, as well as most oth...

Towards natural language question generation for the validation of ontologies and mappings.

Journal of biomedical semantics
BACKGROUND: The increasing number of open-access ontologies and their key role in several applications such as decision-support systems highlight the importance of their validation. Human expertise is crucial for the validation of ontologies from a d...

A method for exploring implicit concept relatedness in biomedical knowledge network.

BMC bioinformatics
BACKGROUND: Biomedical information and knowledge, structural and non-structural, stored in different repositories can be semantically connected to form a hybrid knowledge network. How to compute relatedness between concepts and discover valuable but ...

The ontology of medically related social entities: recent developments.

Journal of biomedical semantics
BACKGROUND: The Ontology of Medically Related Social Entities (OMRSE) was initially developed in 2011 to provide a framework for modeling demographic data in Resource Description Framework/Web Ontology Language. It is built upon the Basic Formal Onto...

COMODI: an ontology to characterise differences in versions of computational models in biology.

Journal of biomedical semantics
BACKGROUND: Open model repositories provide ready-to-reuse computational models of biological systems. Models within those repositories evolve over time, leading to different model versions. Taken together, the underlying changes reflect a model's pr...

NeuroRDF: semantic integration of highly curated data to prioritize biomarker candidates in Alzheimer's disease.

Journal of biomedical semantics
BACKGROUND: Neurodegenerative diseases are incurable and debilitating indications with huge social and economic impact, where much is still to be learnt about the underlying molecular events. Mechanistic disease models could offer a knowledge framewo...