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Bioreactors

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Reinforcement learning based temperature control of a fermentation bioreactor for ethanol production.

Biotechnology and bioengineering
Ethanol production is a significant industrial bioprocess for energy. The primary objective of this study is to control the process reactor temperature to get the desired product, that is, ethanol. Advanced model-based control systems face challenges...

Artificial neural network modeling for the prediction, estimation, and treatment of diverse wastewaters: A comprehensive review and future perspective.

Chemosphere
The application of artificial neural networks (ANNs) in the treatment of wastewater has achieved increasing attention, as it enhances the efficiency and sustainability of wastewater treatment plants (WWTPs). This paper explores the application of ANN...

Explainable machine learning-driven predictive performance and process parameter optimization for caproic acid production.

Bioresource technology
In this study, four machine learning (ML) prediction models were developed to predict and optimize the production performance of caproic acid based on substrates, products, and process parameters. The XGBoost outperformed others, with a high R of 0.9...

Sludge bound-EPS solubilization enhance CH bioconversion and membrane fouling mitigation in electrochemical anaerobic membrane bioreactor: Insights from continuous operation and interpretable machine learning algorithms.

Water research
Bound extracellular polymeric substances (EPS) are complex, high-molecular-weight polymer mixtures that play a critical role in pore clogging, foulants adhesion, and fouling layer formation during membrane filtration, owing to their adhesive properti...

Supporting data-enhanced hybrid ordinary differential equation model for phosphate dynamics in municipal wastewater treatment.

Bioresource technology
A parallel hybrid ordinary differential equation (ODE) integrating the Activated Sludge Model No. 2d (ASM2d) and an artificial neural network (ANN) was developed to simulate biological phosphorus removal (BPR) with high accuracy and interpretability....

Transition from sulfur autotrophic to mixotrophic denitrification: Performance with different carbon sources, microbial community and artificial neural network modeling.

Chemosphere
To address the limitations inherent in both sulfur autotrophic denitrification (SAD) and heterotrophic denitrification (HD) processes, this study introduces a novel approach. Three carbon sources (glucose, methanol, and sodium acetate) were fed into ...

Physics-informed neural networks for biopharmaceutical cultivation processes: Consideration of varying process parameter settings.

Biotechnology and bioengineering
We present a new modeling approach for the study and prediction of important process outcomes of biotechnological cultivation processes under the influence of process parameter variations. Our model is based on physics-informed neural networks (PINNs...

Exploring interactive effects of environmental and microbial factors on food waste anaerobic digestion performance: Interpretable machine learning models.

Bioresource technology
Biogas yield in anaerobic digestion (AD) involves continuous and complex biological reactions. The traditional linear models failed to quantitatively assess the interactive effects of these factors on AD performance. To further explore the internal r...

Machine learning for enhancing prediction of biogas production and building a VFA/ALK soft sensor in full-scale dry anaerobic digestion of kitchen food waste.

Journal of environmental management
Based on operational data collected over 1.5 years from four full-scale dry anaerobic digesters used for kitchen food waste treatment, this study adopted eight typical machine learning algorithms to distinguish the best biogas prediction model and to...

Machine learning-based prediction of non-aeration linear alkylbenzene sulfonate mineralization in an oxygenic microalgal-bacteria biofilm.

Bioresource technology
Microalgal-bacteria biofilm shows great potential in low-cost greywater treatment. Accurately predicting treated greywater quality is of great significance for water reuse. In this work, machine learning models were developed for simulating and predi...