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Biofilms

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Antibacterial and antibiofilm activities of star anise-cinnamon essential oil against multidrug-resistant Thompson.

Frontiers in cellular and infection microbiology
INTRODUCTION: The emergence of foodborne multidrug-resistant (MDR) has attracted considerable global attention. Given that food is the primary transmission route, our study focuses on , a freshwater snail that is commonly consumed as a specialty foo...

CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms.

Frontiers in cellular and infection microbiology
INTRODUCTION: Accurately assessing biofilm viability is essential for evaluating both biofilm formation and the efficacy of antibacterial treatments. Traditional SYTO9 and propidium iodide (PI) live/dead staining in biofilm viability assays often ace...

Facile phyto-mediated synthesis of ternary CuO/MnO/ZnO nanocomposite using Nigella Sativa seeds extract: characterization,antimicrobial, and biomedical evaluations.

Scientific reports
The phyto-synthesis of ternary CuO/ MnO/ZnO nanocomposite was achieved by the utilization of an eco-friendly, straightforward approach that involved the extract of Nigella sativa seeds. Our ternary nanocomposite appears to include equal amounts of Cu...

Analysis of biofilm assembly by large area automated AFM.

NPJ biofilms and microbiomes
Biofilms are complex microbial communities critical in medical, industrial, and environmental contexts. Understanding their assembly, structure, genetic regulation, interspecies interactions, and environmental responses is key to developing effective...

4-Hydroxyboesenbergin B of Alpinia japonica protected gastrointestinal tract by inhibiting vancomycin-resistant enterococcus and balancing intestinal microbiota.

Journal of ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE: Alpinia japonica, a traditional herb utilized in Miao medicine in southwestern China, has been employed to alleviate symptoms such as stomachache, diarrhea, and abdominal pain, some of these symptoms may be associated ...

Study of interaction in dual-species biofilm of Candida glabrata and Klebsiella pneumoniae co-isolated from peripheral venous catheter using Raman characterization mapping and machine learning algorithms.

Microbial pathogenesis
Polymicrobial biofilm infections, especially associated with medical devices such as peripheral venous catheters, are challenging in clinical settings for treatment and management. In this study, we examined the mixed biofilm formed by Candida glabra...

ML-AMPs designed through machine learning show antifungal activity against C. albicans and therapeutic potential on mice model with candidiasis.

Life sciences
AIMS: C. albicans resistant strains have led to increasingly severe treatment challenges. Antimicrobial peptides with low resistance-inducing propensity for pathogens have been developed. A series of antimicrobial peptides de novo designed through ma...

Biofilm-mediated infections; novel therapeutic approaches and harnessing artificial intelligence for early detection and treatment of biofilm-associated infections.

Microbial pathogenesis
A biofilm is a group of bacteria that have self-produced a matrix and are grouped together in a dense population. By resisting the host's immune system's phagocytosis process and attacking with anti-microbial chemicals such as reactive oxygen and nit...

Liquid-bodied antibiofilm robot with switchable viscoelastic response for biofilm eradication on complex surface topographies.

Science advances
Recalcitrant biofilm infections pose a great challenge to human health. Micro- and nanorobots have been used to eliminate biofilm infections in hard-to-reach regions inside the body. However, applying antibiofilm robots under physiological conditions...

Intelligent biofilm detection with ensemble of deep learning networks.

Medicina oral, patologia oral y cirugia bucal
BACKGROUND: Dental biofilm is traditionally identified visually, which can be challenging and time-consuming due to its color similarity with the tooth. The aim of this study was to evaluate the performance of U-Net neural networks for the automatic ...