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Butyric Acid

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Butyric acid alleviates LPS-induced intestinal mucosal barrier damage by inhibiting the RhoA/ROCK2/MLCK signaling pathway in Caco2 cells.

PloS one
Butyric acid (BA) can potentially enhance the function of the intestinal barrier. However, the mechanisms by which BA protects the intestinal mucosal barrier remain to be elucidated. Given that the Ras homolog gene family, member A (RhoA)/Rho-associa...

Hantzsch pre-column derivatization for simultaneous determination of alendronate sodium and its pharmacopoeial related impurity: Comparative study with synchronous fluorometry using fluorescamine.

Journal of food and drug analysis
High performance liquid chromatographic (HPLC) method with a pre-column derivatization based on Hantzsch condensation reaction was applied for simultaneous determination of alendronate sodium (ALN) and its main related impurity, 4-Aminobutanoic acid ...

Ultrasound enhanced butyric acid-lauric acid designer lipid synthesis: Based on artificial neural network and changes in enzymatic structure.

Ultrasonics sonochemistry
Ultrasound is a green technology for intensifying enzymatic reactions. In this study, an ultrasonic water bath with equipment parameters of 28 kHz, 1750.1 W/m, 60% duty cycle was used to assist the synthesis of butyric acid-lauric acid designer lipid...

Explainable machine learning-driven predictive performance and process parameter optimization for caproic acid production.

Bioresource technology
In this study, four machine learning (ML) prediction models were developed to predict and optimize the production performance of caproic acid based on substrates, products, and process parameters. The XGBoost outperformed others, with a high R of 0.9...