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Bioreactors

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Combined effects of volume ratio and nitrate recycling ratio on nutrient removal, sludge characteristic and microbial evolution for DPR optimization.

Journal of environmental sciences (China)
The optimization of volume ratio (V/V/V) and nitrate recycling ratio (R) in a two-sludge denitrifying phosphorus removal (DPR) process of Anaerobic Anoxic Oxic-Moving Bed Biofilm Reactor (A/O-MBBR) was investigated. The results showed that prolonged ...

A robust soft sensor to monitor 1,3-propanediol fermentation process by Clostridium butyricum based on artificial neural network.

Biotechnology and bioengineering
With the aggravation of environmental pollution and energy crisis, the sustainable microbial fermentation process of converting glycerol to 1,3-propanediol (1,3-PDO) has become an attractive alternative. However, the difficulty in the online measurem...

Modeling water flux in osmotic membrane bioreactor by adaptive network-based fuzzy inference system and artificial neural network.

Bioresource technology
Osmotic Membrane Bioreactor (OMBR) is an emerging technology for wastewater treatment with membrane fouling as a major challenge. This study aims to develop Adaptive Network-based Fuzzy Inference System (ANFIS) and Artificial Neural Network (ANN) mod...

Machine learning-aided analyses of thousands of draft genomes reveal specific features of activated sludge processes.

Microbiome
BACKGROUND: Microorganisms in activated sludge (AS) play key roles in the wastewater treatment processes. However, their ecological behaviors and differences from microorganisms in other environments have mainly been studied using the 16S rRNA gene t...

Quantification of interfacial energies associated with membrane fouling in a membrane bioreactor by using BP and GRNN artificial neural networks.

Journal of colloid and interface science
Interfacial energy between sludge foulants and rough membrane surface critically determines adhesive fouling in membrane bioreactors (MBRs). As a current available method, the advanced extensive Derjaguin-Landau-Verwey-Overbeek (XDLVO) approach canno...

Gas-phase trichloroethylene removal by Rhodococcus opacus using an airlift bioreactor and its modeling by artificial neural network.

Chemosphere
This study evaluated the biological removal of trichloroethylene (TCE) by Rhodococcus opacus using airlift bioreactor under continuous operation mode. The effect of inlet TCE concentration in the range 0.12-2.34 g m on TCE removal has studied for 55 ...

Applications of Computer Modeling and Simulation in Cartilage Tissue Engineering.

Tissue engineering and regenerative medicine
BACKGROUND: Advances in cartilage tissue engineering have demonstrated noteworthy potential for developing cartilage for implantation onto sites impacted by joint degeneration and injury. To supplement resource-intensive in vivo and in vitro studies ...

Increasing productivity of Spirulina platensis in photobioreactors using artificial neural network modeling.

Biotechnology and bioengineering
Although production of microalgae in open ponds is conventionally practiced due to its economy, exposure of the algae to uncontrollable elements impedes achievement of quality and it is desirable to develop closed reactor cultivation methods for the ...

A machine-learning approach to calibrate generic Raman models for real-time monitoring of cell culture processes.

Biotechnology and bioengineering
The manufacture of biotherapeutic proteins consists of complex upstream unit operations requiring multiple raw materials, analytical techniques, and control strategies to produce safe and consistent products for patients. Raman spectroscopy is a ubiq...

Integrated Robotic Mini Bioreactor Platform for Automated, Parallel Microbial Cultivation With Online Data Handling and Process Control.

SLAS technology
During process development, the experimental search space is defined by the number of experiments that can be performed in specific time frames but also by its sophistication (e.g., inputs, sensors, sampling frequency, analytics). High-throughput liq...