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Blastocyst

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A non-invasive artificial intelligence approach for the prediction of human blastocyst ploidy: a retrospective model development and validation study.

The Lancet. Digital health
BACKGROUND: One challenge in the field of in-vitro fertilisation is the selection of the most viable embryos for transfer. Morphological quality assessment and morphokinetic analysis both have the disadvantage of intra-observer and inter-observer var...

Development and validation of deep learning based embryo selection across multiple days of transfer.

Scientific reports
This work describes the development and validation of a fully automated deep learning model, iDAScore v2.0, for the evaluation of human embryos incubated for 2, 3, and 5 or more days. We trained and evaluated the model on an extensive and diverse dat...

An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization.

Scientific data
Medical Assisted Reproduction proved its efficacy to treat the vast majority forms of infertility. One of the key procedures in this treatment is the selection and transfer of the embryo with the highest developmental potential. To assess this potent...

Noninvasive genetic screening: current advances in artificial intelligence for embryo ploidy prediction.

Fertility and sterility
This review discusses the use of artificial intelligence (AI) algorithms in noninvasive prediction of embryo ploidy status for preimplantation genetic testing in in vitro fertilization procedures. The current gold standard, preimplantation genetic te...

How should the best human embryo in vitro be? Current and future challenges for embryo selection.

Minerva obstetrics and gynecology
In-vitro fertilization (IVF) aims at overcoming the causes of infertility and lead to a healthy live birth. To maximize IVF efficiency, it is critical to identify and transfer the most competent embryo within a cohort produced by a couple during a cy...

Comparing performance between clinics of an embryo evaluation algorithm based on time-lapse images and machine learning.

Journal of assisted reproduction and genetics
PURPOSE: This article aims to assess how differences in maternal age distributions between IVF clinics affect the performance of an artificial intelligence model for embryo viability prediction and proposes a method to account for such differences.

Identifying predictors of Day 5 blastocyst utilization rate using an artificial neural network.

Reproductive biomedicine online
RESEARCH QUESTION: Can artificial intelligence identify predictors of an increased Day 5 blastocyst utilization rate (D5BUR), which is one of the most informative key performance indicators in an IVF laboratory?

Interpretable artificial intelligence-assisted embryo selection improved single-blastocyst transfer outcomes: a prospective cohort study.

Reproductive biomedicine online
RESEARCH QUESTION: What is the pregnancy and neonatal outcomes of an interpretable artificial intelligence (AI) model for embryo selection in a prospective clinical trial?

Discard or not discard, that is the question: an international survey across 117 embryologists on the clinical management of borderline quality blastocysts.

Human reproduction (Oxford, England)
STUDY QUESTION: Do embryologists from different European countries agree on embryo disposition decisions ('use' or 'discard') about Day 7 (>144 h post-insemination) and/or low-quality blastocysts (LQB;

An artificial intelligence algorithm for automated blastocyst morphometric parameters demonstrates a positive association with implantation potential.

Scientific reports
Blastocyst selection is primarily based on morphological scoring systems and morphokinetic data. These methods involve subjective grading and time-consuming techniques. Artificial intelligence allows for objective and quick blastocyst selection. In t...