AIMC Topic: Zonula Occludens-1 Protein

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Butyric acid alleviates LPS-induced intestinal mucosal barrier damage by inhibiting the RhoA/ROCK2/MLCK signaling pathway in Caco2 cells.

PloS one Dec 26, 2024
Butyric acid (BA) can potentially enhance the function of the intestinal barrier. However, the mechanisms by which BA protects the intestinal mucosal barrier remain to be elucidated. Given that the Ras homolog gene family, member A (RhoA)/Rho-associa...
Humans Signal Transduction Lipopolysaccharides Caco-2 Cells rho-Associated Kinases Myosin-Light-Chain Kinase rhoA GTP-Binding Protein Intestinal Mucosa Butyric Acid Occludin Zonula Occludens-1 Protein Pyridines Amides
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Machine-Learning-Based Approach to Decode the Influence of Nanomaterial Properties on Their Interaction with Cells.

ACS applied materials & interfaces Dec 29, 2020
In an nanotoxicity system, cell-nanoparticle (NP) interaction leads to the surface adsorption, uptake, and changes into nuclei/cell phenotype and chemistry, as an indicator of oxidative stress, genotoxicity, and carcinogenicity. Different types of n...
Machine Learning Animals Cell Proliferation Carbon Epithelial Cells Zonula Occludens-1 Protein Gold Metal Nanoparticles Dogs Madin Darby Canine Kidney Cells Tight Junctions Dendrimers Cell Nucleus Actin Cytoskeleton Cell Nucleus Shape
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The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer.

Hormones & cancer Dec 19, 2017
Ovarian cancer is a highly metastatic disease. The metastatic potential is enhanced by epithelial to mesenchymal transition (EMT) in which αvβ3 integrin plays a role. Thyroid hormones (L-thyroxine, T4, and 3,5,3'-triiodo-L-thyronine, T3) bind this in...
Humans Female Cell Line, Tumor Gene Expression Regulation, Neoplastic Signal Transduction Ovarian Neoplasms Zonula Occludens-1 Protein Epithelial-Mesenchymal Transition Thyroxine Cadherins Thyroid Hormones Vimentin Triiodothyronine beta Catenin Integrin alphaVbeta3 Snail Family Transcription Factors Zinc Finger E-box-Binding Homeobox 1
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