AIMC Topic: Cytochrome P-450 CYP11B2

Clear Filters Showing 1 to 2 of 2 articles

ATP2A3 in Primary Aldosteronism: Machine Learning-Based Discovery and Functional Validation.

Hypertension (Dallas, Tex. : 1979)
BACKGROUND: Aldosterone-producing adenomas (APAs) are a common cause of primary aldosteronism that can lead to cardiovascular complications if left untreated. Machine learning-based bioinformatics approaches have emerged as powerful tools for identif...

Modulation of aldosterone levels by aldosterone synthase promoter polymorphism and association with eGFR decline in patients with chronic kidney disease.

Discovery medicine
To determine whether -344T/C CYP11B2 promoter polymorphism affects serum aldosterone levels and whether this polymorphism is an indicator of eGFR decline in patients with chronic kidney disease. -344 C/T CYP11B2 gene polymorphism analysis was perform...