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Dipyridamole

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A potential supplemental indication of dipyridamole for contraception: Dipyridamole inhibits mouse sperm fertilization capacity in vitro.

Biochemical and biophysical research communications
The inhibition of sperm cAMP and ATP levels, using an FDA-approved medication, may impair sperm motility and, consequently, fertilization, thus paving the way for the development of a male contraceptive. The objective of this study was to define the ...

Recent advances in drug repurposing using machine learning.

Current opinion in chemical biology
Drug repurposing aims to find new uses for already existing and approved drugs. We now provide a brief overview of recent developments in drug repurposing using machine learning alongside other computational approaches for comparison. We also highlig...