AIMC Topic: Drug Development

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Unlocking therapeutic frontiers: harnessing artificial intelligence in drug discovery for neurodegenerative diseases.

Drug discovery today
Neurodegenerative diseases (NDs) pose serious healthcare challenges with limited therapeutic treatments and high social burdens. The integration of artificial intelligence (AI) into drug discovery has emerged as a promising approach to address these ...

Artificial intelligence-driven pharmaceutical industry: A paradigm shift in drug discovery, formulation development, manufacturing, quality control, and post-market surveillance.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
The advent of artificial intelligence (AI) has catalyzed a profound transformation in the pharmaceutical industry, ushering in a paradigm shift across various domains, including drug discovery, formulation development, manufacturing, quality control,...

Data-centric challenges with the application and adoption of artificial intelligence for drug discovery.

Expert opinion on drug discovery
INTRODUCTION: Artificial intelligence (AI) is exhibiting tremendous potential to reduce the massive costs and long timescales of drug discovery. There are however important challenges currently limiting the impact and scope of AI models.

Advancing pharmaceutical Intelligence via computationally Prognosticating the in-vitro parameters of fast disintegration tablets using Machine Learning models.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
The field of Machine Learning (ML) has garnered significant attention, particularly in healthcare for predicting disease severity. Recently, the pharmaceutical sector has also adopted ML techniques in various stages of drug development. Tablets are t...

Deep integration of low-cost liquid handling robots in an industrial pharmaceutical development environment.

SLAS technology
The pharmaceutical industry is increasingly embracing laboratory automation to enhance experimental efficiency and operational resilience, particularly through the integration of automated liquid handlers (ALHs). This paper explores the integration o...

The role of artificial intelligence in the development of anticancer therapeutics from natural polyphenols: Current advances and future prospects.

Pharmacological research
Natural polyphenols, abundant in the human diet, are derived from a wide variety of sources. Numerous preclinical studies have demonstrated their significant anticancer properties against various malignancies, making them valuable resources for drug ...

On the Application of Artificial Intelligence/Machine Learning (AI/ML) in Late-Stage Clinical Development.

Therapeutic innovation & regulatory science
Whereas AI/ML methods were considered experimental tools in clinical development for some time, nowadays they are widely available. However, stakeholders in the health care industry still need to answer the question which role these methods can reali...

Accelerating drug discovery, development, and clinical trials by artificial intelligence.

Med (New York, N.Y.)
Artificial intelligence (AI) has profoundly advanced the field of biomedical research, which also demonstrates transformative capacity for innovation in drug development. This paper aims to deliver a comprehensive analysis of the progress in AI-assis...

The Artificial Intelligence-Powered New Era in Pharmaceutical Research and Development: A Review.

AAPS PharmSciTech
Currently, artificial intelligence (AI), machine learning (ML), and deep learning (DL) are gaining increased interest in many fields, particularly in pharmaceutical research and development, where they assist in decision-making in complex situations....

Revolutionizing adjuvant development: harnessing AI for next-generation cancer vaccines.

Frontiers in immunology
With the COVID-19 pandemic, the importance of vaccines has been widely recognized and has led to increased research and development efforts. Vaccines also play a crucial role in cancer treatment by activating the immune system to target and destroy c...