AIMC Topic: Dosage Forms

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Current state of machine learning implementation in pharmaceutical process modeling for oral solid dosage forms.

International journal of pharmaceutics Dec 8, 2025
Driven by the Food and Drug Administration's Quality-by-Design initiative and the advancements of Industry 4.0, the pharmaceutical industry is transitioning from traditional batch manufacturing to advanced manufacturing. This transition requires resh...
Artificial Intelligence Drug Compounding Technology, Pharmaceutical Dosage Forms Administration, Oral Quality Control Machine Learning
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A review of the state-of-the-art: progress in ultrasonic and acoustic techniques for quality assessment in the development and manufacturing of oral solid dosage forms - Part I: theoretical foundations and principles.

International journal of pharmaceutics Nov 24, 2025
Over the past two decades, a diverse array of ultrasonic and acoustic elastic-wave techniques has been developed to non-destructively assess macro- and micro-scale properties of compressed Oral Solid Dosage (OSD) forms. These methods are increasingly...
Chemistry, Pharmaceutical Dosage Forms Ultrasonic Waves Ultrasonics Acoustics Administration, Oral Drug Compounding Technology, Pharmaceutical Quality Control Pharmaceutical Preparations
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3D printed dosage forms, where are we headed?

Expert opinion on drug delivery Jul 24, 2024
INTRODUCTION: 3D Printing (3DP) is an innovative fabrication technology that has gained enormous popularity through its paradigm shifts in manufacturing in several disciplines, including healthcare. In this past decade, we have witnessed the impact o...
Humans Artificial Intelligence Drug Development Printing, Three-Dimensional Pharmaceutical Preparations Precision Medicine Drug Delivery Systems Tablets Drug Approval Technology, Pharmaceutical Dosage Forms
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A comprehensive assessment of machine learning algorithms for enhanced characterization and prediction in orodispersible film development.

International journal of pharmaceutics May 3, 2024
Orodispersible films (ODFs) have emerged as innovative pharmaceutical dosage forms, offering patient-specific treatment through adjustable dosing and the combination of diverse active ingredients. This expanding field generates vast datasets, requiri...
Dosage Forms Administration, Oral Chemistry, Pharmaceutical Drug Delivery Systems Pilot Projects Support Vector Machine Pharmaceutical Preparations Drug Development Machine Learning Algorithms
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Transparent predictive modelling of the twin screw granulation process using a compensated interval type-2 fuzzy system.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Dec 27, 2017
In this research, a new systematic modelling framework which uses machine learning for describing the granulation process is presented. First, an interval type-2 fuzzy model is elicited in order to predict the properties of the granules produced by t...
Stochastic Processes Particle Size Machine Learning Cellulose Models, Chemical Technology, Pharmaceutical Fuzzy Logic Algorithms Drug Compounding Dosage Forms Models, Statistical
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Pharmacokinetic comparison of different flubendazole formulations in pigs: A further contribution to its development as a macrofilaricide molecule.

International journal for parasitology. Drugs and drug resistance Sep 25, 2015
Despite the well established ivermectin activity against microfilaria, the success of human filariasis control programmes requires the use of a macrofilaricide compound. Different in vivo trials suggest that flubendazole (FLBZ), an anthelmintic benzi...
Swine Anthelmintics Injections, Subcutaneous Administration, Oral Carboxymethylcellulose Sodium Mebendazole Animals 2-Hydroxypropyl-beta-cyclodextrin Cross-Over Studies Dosage Forms Polysorbates
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Long-term Stability of Esomeprazole in 5% Dextrose Infusion Polyolefin Bags at 5 degrees C +/- 3 degrees C after Microwave Freeze-thaw Treatment.

International journal of pharmaceutical compounding Jan 1, 2015
To improve quality assurance, security, time management, and cost saving of drug delivery, preparation in advance of intravenous solutions has been developed for several infusion solutions. The objective of this study was to investigate the stability...
Asepsis Glucose Dosage Forms Hydrogen-Ion Concentration Excipients Drug Stability Drug Compounding Chromatography, High Pressure Liquid Microwaves Time Factors Polyenes Cold Temperature Freezing Technology, Pharmaceutical Esomeprazole Infusions, Intravenous Drug Packaging Proton Pump Inhibitors Chemistry, Pharmaceutical Chromatography, Reverse-Phase Spectrophotometry, Ultraviolet Equipment Design
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