Journal of chemical information and modeling
Sep 12, 2025
A carcinogenicity assessment of possibly carcinogenic chemicals (International Agency for Research on Cancer: IARC class 2B) was conducted using a consensus framework constructed from three complementary machine learning models: BiLSTM with MACCS fin...
The JunÃn Lake basin, a critical high-altitude ecosystem in the central Peruvian Andes, faces severe contamination from potentially toxic elements (PTEs) driven by mining activities, agriculture, and urbanization. This study evaluates the spatial dis...
Journal of chemical information and modeling
Jul 25, 2025
Molecular carcinogenicity is a crucial factor in the development of cancer, and accurate prediction of it is vital for cancer prevention, treatment, and drug development. In recent years, deep learning has been applied to predict molecular carcinogen...
The accumulation of organic pollutants in the environment has significantly impacted the lives of flora and fauna, resulting in disruptions in the biological ecosystem. Carcinogenicity has been one of the most alarming adverse effects exhibited by th...
Ecotoxicology and environmental safety
Jun 18, 2025
Polyethylene terephthalate (PET), a polymer widely used in consumer products, has recently been implicated in cancer progression, though its mechanistic underpinnings remain elusive. This multidisciplinary study systematically investigates PET's carc...
Mutation research. Genetic toxicology and environmental mutagenesis
Feb 26, 2025
This study aimed to develop an in silico model for predicting human carcinogenicity using advanced deep learning techniques, specifically Graph Neural Networks (GNN), through a multitask learning (MTL) approach. The MTL framework leveraged auxiliary ...
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Nov 7, 2024
INTRODUCTION: The safety and health of food products are essential in the food industry, and the risk of contamination from various contaminants must be evaluated. Exposure to HMs from the environment (especially food) causes various adverse effects ...
Journal of environmental science and health. Part C, Toxicology and carcinogenesis
Sep 3, 2024
The escalating apprehension surrounding the carcinogenic potential of chemicals emphasizes the imperative need for efficient methods of assessing carcinogenicity. Conventional experimental approaches such as in vitro and in vivo assays, albeit effect...
Expert opinion on drug metabolism & toxicology
May 27, 2024
INTRODUCTION: This review explores the transformative impact of machine learning (ML) on carcinogenicity prediction within drug development. It discusses the historical context and recent advancements, emphasizing the significance of ML methodologies...
The development of a rapid and accurate model for determining the genotoxicity and carcinogenicity of chemicals is crucial for effective cancer risk assessment. This study aims to develop a 1-day, single-dose model for identifying genotoxic hepatocar...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.