AIMC Topic: Drug Industry

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Artificial intelligence in drug development: present status and future prospects.

Drug discovery today
Artificial intelligence (AI) uses personified knowledge and learns from the solutions it produces to address not only specific but also complex problems. Remarkable improvements in computational power coupled with advancements in AI technology could ...

Developing Deep Learning Applications for Life Science and Pharma Industry.

Drug research
Deep Learning has boosted artificial intelligence over the past 5 years and is seen now as one of the major technological innovation areas, predicted to replace lots of repetitive, but complex tasks of human labor within the next decade. It is also e...

Implementation of an artificial neural network as a PAT tool for the prediction of temperature distribution within a pharmaceutical fluidized bed granulator.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
In this study, a novel in-line measurement technique of the air temperature distribution during a granulation process using a conical fluidized bed was designed and built for the purpose of measuring the temperature under the Process Analytical Techn...

Predicting Drug-Target Interactions via Within-Score and Between-Score.

BioMed research international
Network inference and local classification models have been shown to be useful in predicting newly potential drug-target interactions (DTIs) for assisting in drug discovery or drug repositioning. The idea is to represent drugs, targets, and their int...

Risk assessment of supply chain for pharmaceutical excipients with AHP-fuzzy comprehensive evaluation.

Drug development and industrial pharmacy
As the essential components in formulations, pharmaceutical excipients directly affect the safety, efficacy, and stability of drugs. Recently, safety incidents of pharmaceutical excipients posing seriously threats to the patients highlight the necess...

A new modeling approach for quantifying expert opinion in the drug discovery process.

Statistics in medicine
Expert opinion plays an important role when choosing clusters of chemical compounds for further investigation. Often, the process by which the clusters are assigned to the experts for evaluation, the so-called selection process, and the qualitative r...

In pursuit of software solutions for pharmaceutical regulatory affairs: Insights and trends.

Annales pharmaceutiques francaises
With rapid upsurge in technology and digital tools, the existing systems including the healthcare systems, especially the pharmaceutical sector is experiencing the revolution in the flow and management of data. Use of digital tools in pharmaceutical ...

Computational Hit Finding: An Industry Perspective.

Journal of medicinal chemistry
Computational hit finding, particularly virtual screening, has been a mainstay of drug discovery campaigns for decades, providing a cost-efficient complement to wet experiments. Innovation in this space slowed considerably as these approaches converg...

NMR Pure Shift Spectroscopy and Its Potential Applications in the Pharmaceutical Industry.

Chembiochem : a European journal of chemical biology
H nuclear magnetic resonance (NMR) spectroscopy plays an important role in the pharmaceutical industry, but for complex substances, spectral analysis is challenging due to the narrow chemical shift range and signal splitting caused by scalar coupling...