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Drug Resistance, Microbial

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Anticipating antibiotic resistance.

Science (New York, N.Y.)
Machine learning can use clinical history to lower the risk of infection recurrence.

Antibiotic discovery in the artificial intelligence era.

Annals of the New York Academy of Sciences
As the global burden of antibiotic resistance continues to grow, creative approaches to antibiotic discovery are needed to accelerate the development of novel medicines. A rapidly progressing computational revolution-artificial intelligence-offers an...

Prediction and interpretation of antibiotic-resistance genes occurrence at recreational beaches using machine learning models.

Journal of environmental management
Antibiotic-resistant bacteria and antibiotic resistance genes (ARGs) are pollutants of worldwide concern that seriously threaten public health and ecosystems. Machine learning (ML) prediction models have been applied to predict ARGs in beach waters. ...

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database.

Nucleic acids research
The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) sequences and resistance-conferring mutations to provide an informatics framework for annotation a...

Addressing antibiotic resistance: computational answers to a biological problem?

Current opinion in microbiology
The increasing prevalence of infections caused by antibiotic-resistant bacteria is a global healthcare crisis. Understanding the spread of resistance is predicated on the surveillance of antibiotic resistance genes within an environment. Bioinformati...

PLM-ARG: antibiotic resistance gene identification using a pretrained protein language model.

Bioinformatics (Oxford, England)
MOTIVATION: Antibiotic resistance presents a formidable global challenge to public health and the environment. While considerable endeavors have been dedicated to identify antibiotic resistance genes (ARGs) for assessing the threat of antibiotic resi...

Using chronobiology-based second-generation artificial intelligence digital system for overcoming antimicrobial drug resistance in chronic infections.

Annals of medicine
Antimicrobial resistance results from the widespread use of antimicrobial agents and is a significant obstacle to the effectiveness of these agents. Numerous methods are used to overcome this problem with moderate success. Besides efforts of antimicr...