BMC medical informatics and decision making
Nov 6, 2025
BACKGROUND: Adolescent depression is a major public health concern. Physical health indicators are rarely included in risk tools. We examined whether adding dry eye disease (DED) to psychosocial and behavioral factors improves prediction of depressiv...
Analytical methods : advancing methods and applications
Aug 21, 2025
Dry eye disease (DED) and depression exhibit high comorbidity, yet lipid and purine diagnostic biomarkers for depression-related DED remain unidentified. In this study, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI)...
The purpose of this study is to examine and interpret machine learning models that predict dry eye (DE)-related clinical signs, subjective symptoms, and clinician diagnoses by heavily weighting lifestyle factors in the predictions. Machine learning m...
PURPOSE: To evaluate and compare subbasal corneal nerve parameters of the inferior whorl in patients with dry eye disease (DED), neuropathic corneal pain (NCP), and controls using a novel deep-learning-based algorithm to analyze in-vivo confocal micr...
PURPOSE: Clinical diagnosis of dry eye disease is based on a subjective Ocular Surface Disease Index questionnaire or various objective tests, however, these diagnostic methods have several limitations.
In the realm of ophthalmology, precise measurement of tear film break-up time (TBUT) plays a crucial role in diagnosing dry eye disease (DED). This study aims to introduce an automated approach utilizing artificial intelligence (AI) to mitigate subje...
IEEE transactions on neural networks and learning systems
Apr 4, 2024
Computer vision syndrome causes vision problems and discomfort mainly due to dry eye. Several studies show that dry eye in computer users is caused by a reduction in the blink rate and an increase in the prevalence of incomplete blinks. In this conte...
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Mar 25, 2024
PURPOSE: This study addressed the utilisation of machine learning techniques to estimate tear osmolarity, a clinically significant yet challenging parameter to measure accurately. Elevated tear osmolarity has been observed in contact lens wearers and...
There is an increasing need for an objective grading system to evaluate the severity of dry eye disease (DED). In this study, a fully automated deep learning-based system for the assessment of DED severity was developed. Corneal fluorescein staining ...
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