OBJECTIVE: This study aimed to establish an optimal model based on machine learning (ML) to predict Valproic acid (VPA) trough concentrations in Chinese adult epilepsy patients.
IEEE transactions on bio-medical engineering
Jan 21, 2025
UNLABELLED: Epilepsy is a neurological disorder characterized by recurrent epileptic seizures, which are often unpredictable and increase mortality and morbidity risks.
OBJECTIVE: Whereas a scalp electroencephalogram (EEG) is important for diagnosing epilepsy, a single routine EEG is limited in its diagnostic value. Only a small percentage of routine EEGs show interictal epileptiform discharges (IEDs) and overall mi...
BMC medical informatics and decision making
Jan 6, 2025
BACKGROUND: The diagnosis and treatment of epilepsy continue to face numerous challenges, highlighting the urgent need for the development of rapid, accurate, and non-invasive methods for seizure detection. In recent years, advancements in the analys...
The rate of success of epilepsy surgery, ensuring seizure-freedom, is limited by the lack of epileptogenicity biomarkers. Previous evidence supports the critical role of functional connectivity during seizure generation to characterize the epileptoge...
. Accurate seizure prediction could prove critical for improving patient safety and quality of life in drug-resistant epilepsy. While deep learning-based approaches have shown promising performance using scalp electroencephalogram (EEG) signals, the ...
Mathematical biosciences and engineering : MBE
Dec 25, 2024
Epileptic seizures, a prevalent neurological condition, necessitate precise and prompt identification for optimal care. Nevertheless, the intricate characteristics of electroencephalography (EEG) signals, noise, and the want for real-time analysis re...
International journal of neural systems
Dec 23, 2024
In the last few decades, Artificial Neural Networks have become more and more important, evolving into a powerful tool to implement learning algorithms. Spiking neural networks represent the third generation of Artificial Neural Networks; they have e...
Interictal epileptiform discharges (IEDs) such as spikes and sharp waves represent pathological electrophysiological activities occurring in epilepsy patients between seizures. IEDs occur preferentially during non-rapid eye movement (NREM) sleep and ...
BACKGROUND: Fast-ripples (FR) are short (∼10 ms) high-frequency oscillations (HFO) between 200 and 600 Hz that are helpful in epilepsy to identify the epileptogenic zone. Our aim is to propose a new method to detect FR that had to be efficient for in...
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