AIMC Topic: Epitopes

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Time series computational prediction of vaccines for influenza A H3N2 with recurrent neural networks.

Journal of bioinformatics and computational biology Feb 1, 2020
Influenza viruses are persistently threatening public health, causing annual epidemics and sporadic pandemics due to rapid viral evolution. Vaccines are used to prevent influenza infections but the composition of the influenza vaccines have to be upd...
Humans Influenza, Human Influenza Vaccines Computational Biology Neural Networks, Computer Influenza A Virus, H3N2 Subtype Epitopes Interrupted Time Series Analysis Mutation Rate Viral Proteins
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Complex Network Study of the Immune Epitope Database for Parasitic Organisms.

Current topics in medicinal chemistry Feb 9, 2018
BACKGROUND: Complex network approach allows the representation and analysis of complex systems of interacting agents in an ordered and effective manner, thus increasing the probability of discovering significant properties of them. In the present stu...
Animals Epitopes Databases, Factual Neural Networks, Computer Data Mining Amino Acid Sequence Parasites
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Identification of errors in the IEDB using ontologies.

Database : the journal of biological databases and curation Jan 1, 2018
The Immune Epitope Database (IEDB) is a free online resource that has manually curated over 18 500 references from the scientific literature. Our database presents experimental data relating to the recognition of immune epitopes by the adaptive immun...
Data Curation Scientific Experimental Error Biological Ontologies Epitopes Databases, Factual
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FAIR principles and the IEDB: short-term improvements and a long-term vision of OBO-foundry mediated machine-actionable interoperability.

Database : the journal of biological databases and curation Jan 1, 2018
The Immune Epitope Database (IEDB), at www.iedb.org, has the mission to make published experimental data relating to the recognition of immune epitopes easily available to the scientific public. By presenting curated data in a searchable database, we...
Biological Ontologies Data Curation Epitopes Humans Animals Databases, Factual
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HLA class I binding prediction via convolutional neural networks.

Bioinformatics (Oxford, England) Sep 1, 2017
MOTIVATION: Many biological processes are governed by protein-ligand interactions. One such example is the recognition of self and non-self cells by the immune system. This immune response process is regulated by the major histocompatibility complex ...
Neural Networks, Computer Peptides Machine Learning Histocompatibility Antigens Class I Proteomics Humans Protein Binding Epitopes HLA Antigens
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Better living through ontologies at the Immune Epitope Database.

Database : the journal of biological databases and curation Jan 1, 2017
UNLABELLED: The Immune Epitope Database (IEDB) project incorporates independently developed ontologies and controlled vocabularies into its curation and search interface. This simplifies curation practices, improves the user query experience and faci...
Vocabulary, Controlled Biological Ontologies Databases, Factual Epitopes
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[Development, identification and application of 33 monoclonal antibodies against cardiac troponin T].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology Dec 25, 2016
The aim of this study is to prepare and characterize cardiac troponin T (cTnT) monoclonal antibodies (mAb), and further develop a chemiluminescence quantitative detection assay for cTnT. BALB/c mice were immunized with recombinant cTnT antigen, and s...
Myocardial Infarction Antibodies, Monoclonal Troponin T Peptide Fragments Epitopes Luminescent Measurements Sensitivity and Specificity Hybridomas Humans Enzyme-Linked Immunosorbent Assay
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