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Hybridomas

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[Preparation of monoclonal antibody against cystatin C and establishment of its immunoassay system].

Wei sheng yan jiu = Journal of hygiene research
OBJECTIVE: To prepare human cystatin C( CysC) recombinant protein and produce monoclonal antibodies with high affinity and specificity. Develop a competitive ELISA detection system to detect of CysC in human serum.

[Development, identification and application of 33 monoclonal antibodies against cardiac troponin T].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
The aim of this study is to prepare and characterize cardiac troponin T (cTnT) monoclonal antibodies (mAb), and further develop a chemiluminescence quantitative detection assay for cTnT. BALB/c mice were immunized with recombinant cTnT antigen, and s...

[Bactericidal Activity of Constructed Recombinant Fusion Protein Pheromonicin-CT].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
OBJECTIVE: To construct engineering peptide pheromonicin-Clostrzaum tretant krn-ui), and to test its bactericidal activity.

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning.

Nature biomedical engineering
The optimization of therapeutic antibodies is time-intensive and resource-demanding, largely because of the low-throughput screening of full-length antibodies (approximately 1 × 10 variants) expressed in mammalian cells, which typically results in fe...