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Fallopia multiflora

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Identification and characterization of the structure-activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum.

Scientific reports 29263357
The adverse effects of Polygonum (P.) multiflorum, including abnormal bilirubin metabolism, are a serious public health issue. As uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) is the only enzyme responsible for bilirubin metabolism, ...
Animals Anthraquinones Chromatography, High Pressure Liquid Fallopia multiflora Glucuronosyltransferase Glycosides In Vitro Techniques Male Microsomes, Liver Plant Extracts Plant Roots Rats Rats, Sprague-Dawley Structure-Activity Relationship
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