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Anthraquinones

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Chitosan-gum arabic embedded alizarin nanocarriers inhibit biofilm formation of multispecies microorganisms.

Carbohydrate polymers
Biofilm formation by microorganisms is a serious clinical problem that leads to drug failure. Nanocarriers (NCs) have shown good potential for controlling drug-resistant biofilms, although the effective penetration and retention of NCs in biofilms is...

Identification and characterization of the structure-activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum.

Scientific reports
The adverse effects of Polygonum (P.) multiflorum, including abnormal bilirubin metabolism, are a serious public health issue. As uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) is the only enzyme responsible for bilirubin metabolism, ...

Investigation of the mutagenic and genotoxic activities of LLL-3, a STAT3 inhibitor.

Drug and chemical toxicology
LLL-3, an anthracene derived compound, has been shown to be a promising therapeutic agent for the treatment of some kinds of cancer such as chronic myeloid leukemia and glioblastoma. However, no data regarding the toxic properties of this compound ha...

Investigation of six bioactive anthraquinones in slimming tea by accelerated solvent extraction and high performance capillary electrophoresis with diode-array detection.

Food chemistry
A rapid and effective method for effective separation and rapid simultaneous determination of six bioactive anthraquinones by capillary zone electrophoresis was developed. An accelerated solvent extraction procedure was used for the extraction of ant...

Optimization of fungi co-fermentation for improving anthraquinone contents and antioxidant activity using artificial neural networks.

Food chemistry
The fermentation products of edible fungi are rich in anthraquinones and have a variety of activities, including the antioxidant activity. Because of the large number of combinations, it is very difficult to obtain the optimal multi-strains co-fermen...

Deep-learning-assisted chemo-responsive alizarin red S-based hydrogel sensor for the rapid freshness sensing of aquatic product.

Food research international (Ottawa, Ont.)
Rapid detection of freshness particularly in aquatic products demands efficient sensing strategies. Here, a novel deep-learning-assisted chemo-responsive alizarin red S-based hydrogel sensing platform was established for rapid freshness assay of aqua...