In contrast to recessive conditions with biallelic inheritance, identification of dominant (monoallelic) mutations for Mendelian disorders is more difficult, because of the abundance of benign heterozygous variants that act as massive background nois...
The study of Mendelian diseases and the identification of their causative genes are of great significance in the field of genetics. The evaluation of the pathogenicity of genes and the total number of Mendelian disease genes are both important questi...
The aim of this study was to compare the predictive performance of the Genomic Best Linear Unbiased Predictor (GBLUP) and machine learning methods (Random Forest, RF; Support Vector Machine, SVM; Artificial Neural Network, ANN) in simulated populatio...