AIMC Topic: Genomics

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Robust automatic breast cancer staging using a combination of functional genomics and image-omics.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Breast cancer is one of the leading cancers worldwide. Precision medicine is a new trend that systematically examines molecular and functional genomic information within each patient's cancer to identify the patterns that may affect treatment decisio...

A Machine Learning Approach for Accurate Annotation of Noncoding RNAs.

IEEE/ACM transactions on computational biology and bioinformatics
Searching genomes to locate noncoding RNA genes with known secondary structure is an important problem in bioinformatics. In general, the secondary structure of a searched noncoding RNA is defined with a structure model constructed from the structura...

An integrated machine-learning model to predict prokaryotic essential genes.

Methods in molecular biology (Clifton, N.J.)
Essential genes are indispensable for the target organism's survival. Large-scale identification and characterization of essential genes has shown to be beneficial in both fundamental biology and medicine fields. Current existing genome-scale experim...

Computer-based prediction of mitochondria-targeting peptides.

Methods in molecular biology (Clifton, N.J.)
Computational methods are invaluable when protein sequences, directly derived from genomic data, need functional and structural annotation. Subcellular localization is a feature necessary for understanding the protein role and the compartment where t...