AIMC Topic: Glutathione S-Transferase pi

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Integrating multi-omics and machine learning to decipher the role of GSTP1 in endocrine-disrupting chemical-induced prostate cancer pathogenesis.

European journal of pharmacology Nov 5, 2025
Prostate cancer (PCa) pathogenesis involves complex interactions between genetic susceptibility and exposure to endocrine-disrupting chemicals (EDCs). This study aimed to systematically identify key genes linking EDC exposure to PCa using an integrat...
Humans Machine Learning Male Molecular Docking Simulation Gene Expression Profiling Transcriptome Multiomics Gene Expression Regulation, Neoplastic Prostatic Neoplasms Endocrine Disruptors Glutathione S-Transferase pi
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Machine learning approaches and genetic determinants that influence the development of type 2 diabetes mellitus: a genetic association study in Brazilian patients.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas Dec 2, 2024
This genetic association study including 120 patients with type 2 diabetes mellitus (T2DM) and 166 non-diabetic individuals aimed to investigate the association of polymorphisms in the genes GSTM1 and GSTT1 (gene deletion), GSTP1 (rs1695), ACE (rs464...
Humans Machine Learning Female Risk Factors Aged Adult Male Middle Aged Brazil Case-Control Studies Diabetes Mellitus, Type 2 Genetic Predisposition to Disease Polymorphism, Single Nucleotide Genotype Genetic Association Studies Vascular Endothelial Growth Factor A Glutathione Transferase Polymorphism, Genetic Glutathione S-Transferase pi
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