AIMC Topic: Heart Failure

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Sacubitril/Valsartan in an Elderly Patient with Heart Failure: A Case Report.

Cardiology
Sacubitril/valsartan has recently been approved for the treatment of heart failure with reduced ejection fraction. Given its recent introduction in the armamentarium for the treatment of heart failure (HF), "field-practice" evidence is required to de...

Estimating causal effects for survival (time-to-event) outcomes by combining classification tree analysis and propensity score weighting.

Journal of evaluation in clinical practice
RATIONALE, AIMS AND OBJECTIVES: A common approach to assessing treatment effects in nonrandomized studies with time-to-event outcomes is to estimate propensity scores and compute weights using logistic regression, test for covariate balance, and then...

Serum vitamin D deficiency and risk of hospitalization for heart failure: Prospective results from the Moli-sani study.

Nutrition, metabolism, and cardiovascular diseases : NMCD
BACKGROUND AND AIMS: Evidence indicates that Vitamin D deficiency may be associated with increased risk of cardiovascular disease, although findings on risk of heart failure (HF) are controversial. We investigated the relationship between serum Vitam...

Subclinical Hypothyroidism Is Associated With Adverse Prognosis in Heart Failure Patients.

The Canadian journal of cardiology
BACKGROUND: It is widely recognized that overt hyper- as well as hypothyroidism are potential causes of heart failure (HF). Additionally it has been recently reported that subclinical hypothyroidism (sub-hypo) is associated with atherosclerosis, deve...

Early Identification of Patients With Acute Decompensated Heart Failure.

Journal of cardiac failure
BACKGROUND: Interventions to reduce readmissions after acute heart failure hospitalization require early identification of patients. The purpose of this study was to develop and test accuracies of various approaches to identify patients with acute de...

Osteopathic manual therapy in heart failure patients: A randomized clinical trial.

Journal of bodywork and movement therapies
BACKGROUND: Heart Failure (HF) patients usually present with increased arterial resistance and reduced blood pressure (BP) leading to an impaired functional capacity. Osteopathic Manual Therapy (OMT) focused on myofascial release techniques (MRT) and...

Text Mining of the Electronic Health Record: An Information Extraction Approach for Automated Identification and Subphenotyping of HFpEF Patients for Clinical Trials.

Journal of cardiovascular translational research
Precision medicine requires clinical trials that are able to efficiently enroll subtypes of patients in whom targeted therapies can be tested. To reduce the large amount of time spent screening, identifying, and recruiting patients with specific subt...

An Implantable Extracardiac Soft Robotic Device for the Failing Heart: Mechanical Coupling and Synchronization.

Soft robotics
Soft robotic devices have significant potential for medical device applications that warrant safe synergistic interaction with humans. This article describes the optimization of an implantable soft robotic system for heart failure whereby soft actuat...