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Herb-Drug Interactions

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Effect of Wuziyanzong pill on metabolism of dapoxetine in vivo and in vitro.

Journal of pharmaceutical and biomedical analysis
In vitro incubation of rat liver microsomes with 30 μL of 100 μmol·L dapoxetine and 30 μL of 10, 100, 250, 500, 1000, 2500, or 5000 μg·mL Wuziyanzong pill was performed at 37 °C for 60 min. Dapoxetine concentration was analyzed by high performance li...

Detecting Signals of Interactions Between Warfarin and Dietary Supplements in Electronic Health Records.

Studies in health technology and informatics
Drug and supplement interactions (DSIs) have drawn widespread attention due to their potential to affect therapeutic response and adverse event risk. Electronic health records provide a valuable source where the signals of DSIs can be identified and ...

HDI Highlighter, The First Intelligent Tool to Screen the Literature on Herb-Drug Interactions.

Clinical pharmacokinetics
Herbal food supplements are commonly used and can be an important part of patient self-care. Like all other bio-active and therapeutic products, they have a benefit/risk balance. These products are not without adverse effects and potentially interact...

[Not Available].

Recenti progressi in medicina
This study explores the potential use of ChatGPT, an AI-based language model, in assessing herbal-drug interactions (HDi) to enhance clinical decision-making. HDi can pose significant health risks by reducing drug efficacy or causing unwanted side ef...