AIMC Topic: HLA-DRB1 Chains

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HLA-DR4Pred2: An improved method for predicting HLA-DRB1*04:01 binders.

Methods (San Diego, Calif.) Oct 19, 2024
HLA-DRB1*04:01 is associated with numerous diseases, including sclerosis, arthritis, diabetes, and COVID-19, emphasizing the need to scan for binders in the antigens to develop immunotherapies and vaccines. Current prediction methods are often limite...
Humans Machine Learning Software COVID-19 SARS-CoV-2 Protein Binding Computational Biology HLA-DRB1 Chains
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NNAlign: a platform to construct and evaluate artificial neural network models of receptor-ligand interactions.

Nucleic acids research Jul 3, 2017
Peptides are extensively used to characterize functional or (linear) structural aspects of receptor-ligand interactions in biological systems, e.g. SH2, SH3, PDZ peptide-recognition domains, the MHC membrane receptors and enzymes such as kinases and ...
Humans Neural Networks, Computer Software Algorithms Peptides Protein Binding Databases, Protein Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Internet Forkhead Transcription Factors Amino Acid Sequence Ligands Cell Cycle Proteins Binding Sites Trans-Activators Sequence Alignment HLA-A1 Antigen HLA-B7 Antigen HLA-B8 Antigen HLA-DRB1 Chains
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