AIMC Topic: HLA-DRB1 Chains

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Decoding the molecular and cellular aspects of multiple sclerosis: From diagnosis to therapeutic strategies.

Brain research
Multiple sclerosis (MS) is a multifaceted, chronic neuroinflammatory condition of the central nervous system (CNS) marked by demyelination, gliosis, and axonal degradation. Despite the comprehensive investigation, the exact etiology remains unclear, ...

HLA-DR4Pred2: An improved method for predicting HLA-DRB1*04:01 binders.

Methods (San Diego, Calif.)
HLA-DRB1*04:01 is associated with numerous diseases, including sclerosis, arthritis, diabetes, and COVID-19, emphasizing the need to scan for binders in the antigens to develop immunotherapies and vaccines. Current prediction methods are often limite...