AIMC Topic: Hydrazones

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Bioactive-guided structural optimization of 1,2,3-triazole phenylhydrazones as potential fungicides against Fusarium graminearum.

Pesticide biochemistry and physiology Dec 19, 2019
The phytopathogenic fungus Fusarium graminearum is the major causal agent of fusarium head blight (FHB), which is one of the most serious diseases in wheat. Based on our previous work, the 1,2,3-triazole phenylhydrazone scaffold was further optimized...
Fungicides, Industrial Fusarium Triazoles Plant Diseases Hydrazones
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G-Protein-Coupled Receptor 35 Mediates Human Saphenous Vein Vascular Smooth Muscle Cell Migration and Endothelial Cell Proliferation.

Journal of vascular research Apr 12, 2016
Vascular smooth muscle cell (VSMC) migration and proliferation is central to neointima formation in vein graft failure following coronary artery bypass. However, there are currently no pharmacological interventions that prevent vein graft failure thr...
Humans Time Factors Cell Proliferation Signal Transduction Cell Movement Dose-Response Relationship, Drug Receptors, G-Protein-Coupled rho-Associated Kinases rhoA GTP-Binding Protein Muscle, Smooth, Vascular Thiazolidines Hydrazones Thiourea HEK293 Cells Myocytes, Smooth Muscle Endothelial Cells Actin Cytoskeleton Aminosalicylic Acids Naphthols Purinones Saphenous Vein
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