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Thiourea

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Graphene quantum dots as singlet oxygen producer or radical quencher - The matter of functionalization with urea/thiourea.

Materials science & engineering. C, Materials for biological applications
Due to their low cost and possible green synthesis, high stability and resistance to photobleaching, graphene quantum dots (GQDs) can be considered as one of the class of carbon nanomaterials which may have great potential as an agent for photosensit...

Synthesis and Evaluation of Biological Activities of Aziridine Derivatives of Urea and Thiourea.

Molecules (Basel, Switzerland)
In the present paper, we report the synthesis and evaluation of in vitro antimicrobial activities of aziridine-thiourea derivatives. A series of aziridines in reaction with isocyanates and isothiocyanates to obtain urea and thiourea derivatives were ...

Machine Learning augmented docking studies of aminothioureas at the SARS-CoV-2-ACE2 interface.

PloS one
The current pandemic outbreak clearly indicated the urgent need for tools allowing fast predictions of bioactivity of a large number of compounds, either available or at least synthesizable. In the computational chemistry toolbox, several such tools ...

Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter.

International journal of molecular sciences
Through a combination of comparative modeling, site-directed and classical random mutagenesis approaches, we previously identified critical residues for binding, recognition, and translocation of urea, and its inhibition by 2-thiourea and acetamide i...