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Immunity, Humoral

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CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus.

Iranian journal of allergy, asthma, and immunology 30644702
Among many pneumococcal antigens, choline-binding proteins (CPBs) display a high immunogenicity in animal models. This study aims to determine the immunogenicity of CbpM, CbpG and CbpL proteins of Streptococcus pneumoniae in a mice model. The genes w...
Animals Antibodies, Bacterial Bacterial Proteins Female Immunity, Humoral Mice Mice, Inbred BALB C Models, Animal Phagocytosis Pneumococcal Infections Pneumococcal Vaccines Recombinant Proteins Serogroup Streptococcus pneumoniae Vaccination
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Capturing the differences between humoral immunity in the normal and tumor environments from repertoire-seq of B-cell receptors using supervised machine learning.

BMC bioinformatics 31138102
BACKGROUND: The recent success of immunotherapy in treating tumors has attracted increasing interest in research related to the adaptive immune system in the tumor microenvironment. Recent advances in next-generation sequencing technology enabled the...
Algorithms Amino Acid Motifs Amino Acid Sequence Area Under Curve Complementarity Determining Regions Databases, Genetic High-Throughput Nucleotide Sequencing Humans Immunity, Humoral Immunoglobulins Receptors, Antigen, B-Cell ROC Curve Supervised Machine Learning Tumor Microenvironment
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